Stroke depression: a concept with clinical applicability

Jun Mu, Arun V. Ravindran, Pim Cuijpers, Yiqing Shen, Wensong Yang, Qi Li, Xinyu Zhou, Peng Xie*

*Corresponding author for this work

Research output: Contribution to JournalReview articleAcademicpeer-review

Abstract

Stroke is a common neurological condition and among the leading causes of death and disability worldwide. Depression is both a risk factor for and complication of stroke, and the two conditions may have a complex reciprocal relationship over time. However, the secondary effects of depression on stroke are often overlooked, resulting in increased morbidity and mortality. In the previous concept of ‘poststroke depression’, stroke and depression were considered as two independent diseases. It often delays the diagnosis and treatment of patients. The concept ‘stroke depression’ proposed in this article will emphasise more the necessity of aggressive treatment of depression in the overall management of stroke, thus to reduce the incidence of stroke and in the meantime, improve the prognosis of stroke. Hopefully, it will lead us into a new era of acute stroke intervention.

Original languageEnglish
Pages (from-to)189-193
Number of pages5
JournalStroke and Vascular Neurology
Volume9
Issue number3
Early online date4 Oct 2023
DOIs
Publication statusPublished - Jun 2024

Bibliographical note

Publisher Copyright:
© Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

Funding

FundersFunder number
National Key Research and Development Program of China2017YFA0505700
Non-Profit Central Research Institute Fund of the Chinese Academy of Medical Sciences2019PT320002
Natural Science Foundation Project of China81820108015

    Keywords

    • Stroke

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