Abstract
Flavonoids, a group of naturally occurring antioxidants and iron chelators, might be used as cardioprotective agents in doxorubicin-induced cardiotoxicity, which is believed to be caused by the formation of oxygen free radicals. To investigate the underlying molecular mechanism, we tested a large group of flavonoids from all major structural subclasses on their ability to inhibit doxorubicin (enzymatically)-induced and Fe
Original language | English |
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Pages (from-to) | 331-342 |
Journal | Free Radical Biology and Medicine |
Volume | 20 |
Issue number | 3 |
DOIs | |
Publication status | Published - 1996 |