Structural aspects of antioxidant activity of flavonoids.

S.A.B.E. van Acker; D.J. van den Berg; M.N.J.L. Tromp; D.H. Griffioen; W.P. van Bennekom; W.J.F. van der Vijgh; A. Bast

doi:10.1016/0891-5849(95)02047-0

Structural aspects of antioxidant activity of flavonoids.

S.A.B.E. van Acker, D.J. van den Berg, M.N.J.L. Tromp, D.H. Griffioen, W.P. van Bennekom, W.J.F. van der Vijgh, A. Bast

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

Flavonoids, a group of naturally occurring antioxidants and iron chelators, might be used as cardioprotective agents in doxorubicin-induced cardiotoxicity, which is believed to be caused by the formation of oxygen free radicals. To investigate the underlying molecular mechanism, we tested a large group of flavonoids from all major structural subclasses on their ability to inhibit doxorubicin (enzymatically)-induced and Fe

Original language	English
Pages (from-to)	331-342
Journal	Free Radical Biology and Medicine
Volume	20
Issue number	3
DOIs	https://doi.org/10.1016/0891-5849(95)02047-0
Publication status	Published - 1996

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10.1016/0891-5849(95)02047-0

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title = "Structural aspects of antioxidant activity of flavonoids.",

abstract = "Flavonoids, a group of naturally occurring antioxidants and iron chelators, might be used as cardioprotective agents in doxorubicin-induced cardiotoxicity, which is believed to be caused by the formation of oxygen free radicals. To investigate the underlying molecular mechanism, we tested a large group of flavonoids from all major structural subclasses on their ability to inhibit doxorubicin (enzymatically)-induced and Fe",

author = "{van Acker}, S.A.B.E. and {van den Berg}, D.J. and M.N.J.L. Tromp and D.H. Griffioen and {van Bennekom}, W.P. and {van der Vijgh}, W.J.F. and A. Bast",

year = "1996",

doi = "10.1016/0891-5849(95)02047-0",

language = "English",

volume = "20",

pages = "331--342",

journal = "Free Radical Biology and Medicine",

issn = "0891-5849",

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T1 - Structural aspects of antioxidant activity of flavonoids.

AU - van Acker, S.A.B.E.

AU - van den Berg, D.J.

AU - Tromp, M.N.J.L.

AU - Griffioen, D.H.

AU - van Bennekom, W.P.

AU - van der Vijgh, W.J.F.

AU - Bast, A.

PY - 1996

Y1 - 1996

N2 - Flavonoids, a group of naturally occurring antioxidants and iron chelators, might be used as cardioprotective agents in doxorubicin-induced cardiotoxicity, which is believed to be caused by the formation of oxygen free radicals. To investigate the underlying molecular mechanism, we tested a large group of flavonoids from all major structural subclasses on their ability to inhibit doxorubicin (enzymatically)-induced and Fe

AB - Flavonoids, a group of naturally occurring antioxidants and iron chelators, might be used as cardioprotective agents in doxorubicin-induced cardiotoxicity, which is believed to be caused by the formation of oxygen free radicals. To investigate the underlying molecular mechanism, we tested a large group of flavonoids from all major structural subclasses on their ability to inhibit doxorubicin (enzymatically)-induced and Fe

U2 - 10.1016/0891-5849(95)02047-0

DO - 10.1016/0891-5849(95)02047-0

M3 - Article

SN - 0891-5849

VL - 20

SP - 331

EP - 342

JO - Free Radical Biology and Medicine

JF - Free Radical Biology and Medicine

IS - 3

ER -

Structural aspects of antioxidant activity of flavonoids.

Abstract

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