Synthesis and initial preclinical evaluation of the P2X(7) receptor antagonist [C-11]A-740003 as a novel tracer of neuroinflammation

B. Janssen, D.J. Vugts, U. Funke, A. Spaans, R.C. Schuit, E. Kooijman, M. Rongen, L.R. Perk, A.A. Lammertsma, A.D. Windhorst

    Research output: Contribution to JournalArticleAcademicpeer-review

    Abstract

    Neuroinflammation, in particular activation of microglia, is thought to play an important role in the progression of neurodegenerative diseases. In activated microglia, the purinergic P2X
    Original languageEnglish
    Pages (from-to)509-516
    JournalJournal of Labelled Compounds and Radiopharmaceuticals
    Volume57
    Issue number8
    DOIs
    Publication statusPublished - 2014

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