Synthesis and pharmacological evaluation of some amino-acid-containing cyproheptadine derivatives as dual antagonists of histamine H1- and leukotriene D4-receptors.

M.Q. Zhang; A. van de Stolpe; O.P. Zuiderveld; H. Timmerman

doi:10.1016/S0223-5234(97)87535-6

Synthesis and pharmacological evaluation of some amino-acid-containing cyproheptadine derivatives as dual antagonists of histamine H1- and leukotriene D4-receptors.

M.Q. Zhang
, A. van de Stolpe
, O.P. Zuiderveld
, H. Timmerman

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

A novel series of cyproheptadine derivatives, in which an amino acid or a dipeptide moiety was introduced at the piperidine nitrogen, have been synthesized. The amino acid and dipeptide moieties were taken as part of leukotriene D

Original language	English
Pages (from-to)	95-102
Journal	European Journal of Medicinal Chemistry
Volume	32
DOIs	https://doi.org/10.1016/S0223-5234(97)87535-6
Publication status	Published - 1997

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Access to Document

10.1016/S0223-5234(97)87535-6

Persistent URL (handle)

Persistent link

Cite this

@article{a927e6790983459389dab1a793ad2818,

title = "Synthesis and pharmacological evaluation of some amino-acid-containing cyproheptadine derivatives as dual antagonists of histamine H1- and leukotriene D4-receptors.",

abstract = "A novel series of cyproheptadine derivatives, in which an amino acid or a dipeptide moiety was introduced at the piperidine nitrogen, have been synthesized. The amino acid and dipeptide moieties were taken as part of leukotriene D",

author = "M.Q. Zhang and \{van de Stolpe\}, A. and O.P. Zuiderveld and H. Timmerman",

year = "1997",

doi = "10.1016/S0223-5234(97)87535-6",

language = "English",

volume = "32",

pages = "95--102",

journal = "European Journal of Medicinal Chemistry",

issn = "0223-5234",

publisher = "Elsevier Masson s.r.l.",

}

Synthesis and pharmacological evaluation of some amino-acid-containing cyproheptadine derivatives as dual antagonists of histamine H1- and leukotriene D4-receptors. / Zhang, M.Q.; van de Stolpe, A.; Zuiderveld, O.P. et al.
In: European Journal of Medicinal Chemistry, Vol. 32, 1997, p. 95-102.

Research output: Contribution to Journal › Article › Academic › peer-review

TY - JOUR

T1 - Synthesis and pharmacological evaluation of some amino-acid-containing cyproheptadine derivatives as dual antagonists of histamine H1- and leukotriene D4-receptors.

AU - Zhang, M.Q.

AU - van de Stolpe, A.

AU - Zuiderveld, O.P.

AU - Timmerman, H.

PY - 1997

Y1 - 1997

N2 - A novel series of cyproheptadine derivatives, in which an amino acid or a dipeptide moiety was introduced at the piperidine nitrogen, have been synthesized. The amino acid and dipeptide moieties were taken as part of leukotriene D

AB - A novel series of cyproheptadine derivatives, in which an amino acid or a dipeptide moiety was introduced at the piperidine nitrogen, have been synthesized. The amino acid and dipeptide moieties were taken as part of leukotriene D

U2 - 10.1016/S0223-5234(97)87535-6

DO - 10.1016/S0223-5234(97)87535-6

M3 - Article

SN - 0223-5234

VL - 32

SP - 95

EP - 102

JO - European Journal of Medicinal Chemistry

JF - European Journal of Medicinal Chemistry

ER -

Synthesis and pharmacological evaluation of some amino-acid-containing cyproheptadine derivatives as dual antagonists of histamine H1- and leukotriene D4-receptors.

Abstract

UN SDGs

Access to Document

Persistent URL (handle)

Fingerprint

Cite this