Synthesis and structure-activity relationships of conformationally constrained histamine H(3) receptor agonists

R. Kitbunnadaj; O.P. Zuiderveld; I.J. De Esch; R.C. Vollinga; R.A. Bakker; M. Lutz; A.L Spek; E. Cavoy; M.F. Deltent; W.M.P.B. Menge; H. Timmerman; R. Leurs

doi:10.1021/jm030905y

Synthesis and structure-activity relationships of conformationally constrained histamine H(3) receptor agonists

R. Kitbunnadaj, O.P. Zuiderveld, I.J. De Esch, R.C. Vollinga, R.A. Bakker, M. Lutz, A.L Spek, E. Cavoy, M.F. Deltent, W.M.P.B. Menge, H. Timmerman, R. Leurs

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

Immepip, a conformationally constrained analogue of the histamine congener imbutamine, shows high affinity and functional activity on the human H

Original language	English
Pages (from-to)	5445-57
Journal	Journal of Medicinal Chemistry
Volume	46
Issue number	25
DOIs	https://doi.org/10.1021/jm030905y
Publication status	Published - 2003

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10.1021/jm030905y

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CCDC 244630: Experimental Crystal Structure Determination
Kitbunnadaj, R. (Contributor), Zuiderveld, O. P. (Contributor), de Esch, I. (Contributor), Vollinga, R. C. (Contributor), Bakker, R. (Contributor), Lutz, M. (Contributor), Spek, A. L. (Contributor), Cavoy, E. (Contributor), Deltent, M. (Contributor), Menge, W. M. P. B. (Contributor), Timmerman, H. (Contributor) & Leurs, R. (Contributor), Unknown Publisher, 1 Jan 2004
DOI: 10.5517/cc86k99, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/cc86k99&sid=DataCite
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Kitbunnadaj, R., Zuiderveld, O. P., De Esch, I. J., Vollinga, R. C., Bakker, R. A., Lutz, M., Spek, A. L., Cavoy, E., Deltent, M. F., Menge, W. M. P. B., Timmerman, H., & Leurs, R. (2003). Synthesis and structure-activity relationships of conformationally constrained histamine H(3) receptor agonists. Journal of Medicinal Chemistry, 46(25), 5445-57. https://doi.org/10.1021/jm030905y

@article{af6927359a724953b9ca04f853f78ece,

title = "Synthesis and structure-activity relationships of conformationally constrained histamine H(3) receptor agonists",

abstract = "Immepip, a conformationally constrained analogue of the histamine congener imbutamine, shows high affinity and functional activity on the human H",

author = "R. Kitbunnadaj and O.P. Zuiderveld and {De Esch}, I.J. and R.C. Vollinga and R.A. Bakker and M. Lutz and A.L Spek and E. Cavoy and M.F. Deltent and W.M.P.B. Menge and H. Timmerman and R. Leurs",

year = "2003",

doi = "10.1021/jm030905y",

language = "English",

volume = "46",

pages = "5445--57",

journal = "Journal of Medicinal Chemistry",

issn = "0022-2623",

publisher = "American Chemical Society",

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T1 - Synthesis and structure-activity relationships of conformationally constrained histamine H(3) receptor agonists

AU - Kitbunnadaj, R.

AU - Zuiderveld, O.P.

AU - De Esch, I.J.

AU - Vollinga, R.C.

AU - Bakker, R.A.

AU - Lutz, M.

AU - Spek, A.L

AU - Cavoy, E.

AU - Deltent, M.F.

AU - Menge, W.M.P.B.

AU - Timmerman, H.

AU - Leurs, R.

PY - 2003

Y1 - 2003

N2 - Immepip, a conformationally constrained analogue of the histamine congener imbutamine, shows high affinity and functional activity on the human H

AB - Immepip, a conformationally constrained analogue of the histamine congener imbutamine, shows high affinity and functional activity on the human H

U2 - 10.1021/jm030905y

DO - 10.1021/jm030905y

M3 - Article

SN - 0022-2623

VL - 46

SP - 5445

EP - 5457

JO - Journal of Medicinal Chemistry

JF - Journal of Medicinal Chemistry

IS - 25

ER -

Synthesis and structure-activity relationships of conformationally constrained histamine H(3) receptor agonists

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CCDC 244630: Experimental Crystal Structure Determination

Cite this