Synthesis, biological evaluation and automated docking of constrained analogs of the opioid peptide H-Dmt-D-AlapPhe-Gly-NH2 using the 4- or 5-metyl substsituted 4-amino-1,2,3,4-tetrahydro-2-benzazepin-3-one scaffold.

R de Wachter; C. de Graaf; C Keresztes; B Vandormael; S Ballet; G. Toth; D. Rognan; D Tourwé

Synthesis, biological evaluation and automated docking of constrained analogs of the opioid peptide H-Dmt-D-AlapPhe-Gly-NH2 using the 4- or 5-metyl substsituted 4-amino-1,2,3,4-tetrahydro-2-benzazepin-3-one scaffold.

R de Wachter, C. de Graaf, C Keresztes, B Vandormael, S Ballet, G. Toth, D. Rognan, D Tourwé

Research output: Contribution to Journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	3384-3393
Number of pages	10
Journal	Journal of Medicinal Chemistry
Volume	54
Publication status	Published - 2011

Cite this

de Wachter, R., de Graaf, C., Keresztes, C., Vandormael, B., Ballet, S., Toth, G., Rognan, D., & Tourwé, D. (2011). Synthesis, biological evaluation and automated docking of constrained analogs of the opioid peptide H-Dmt-D-AlapPhe-Gly-NH2 using the 4- or 5-metyl substsituted 4-amino-1,2,3,4-tetrahydro-2-benzazepin-3-one scaffold. Journal of Medicinal Chemistry, 54, 3384-3393.

de Wachter, R ; de Graaf, C. ; Keresztes, C ; Vandormael, B ; Ballet, S ; Toth, G. ; Rognan, D. ; Tourwé, D. / Synthesis, biological evaluation and automated docking of constrained analogs of the opioid peptide H-Dmt-D-AlapPhe-Gly-NH2 using the 4- or 5-metyl substsituted 4-amino-1,2,3,4-tetrahydro-2-benzazepin-3-one scaffold. In: Journal of Medicinal Chemistry. 2011 ; Vol. 54. pp. 3384-3393.

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title = "Synthesis, biological evaluation and automated docking of constrained analogs of the opioid peptide H-Dmt-D-AlapPhe-Gly-NH2 using the 4- or 5-metyl substsituted 4-amino-1,2,3,4-tetrahydro-2-benzazepin-3-one scaffold.",

author = "{de Wachter}, R and {de Graaf}, C. and C Keresztes and B Vandormael and S Ballet and G. Toth and D. Rognan and D Tourw{\'e}",

year = "2011",

language = "English",

volume = "54",

pages = "3384--3393",

journal = "Journal of Medicinal Chemistry",

issn = "0022-2623",

publisher = "American Chemical Society",

}

de Wachter, R, de Graaf, C, Keresztes, C, Vandormael, B, Ballet, S, Toth, G, Rognan, D & Tourwé, D 2011, 'Synthesis, biological evaluation and automated docking of constrained analogs of the opioid peptide H-Dmt-D-AlapPhe-Gly-NH2 using the 4- or 5-metyl substsituted 4-amino-1,2,3,4-tetrahydro-2-benzazepin-3-one scaffold.', Journal of Medicinal Chemistry, vol. 54, pp. 3384-3393.

Synthesis, biological evaluation and automated docking of constrained analogs of the opioid peptide H-Dmt-D-AlapPhe-Gly-NH2 using the 4- or 5-metyl substsituted 4-amino-1,2,3,4-tetrahydro-2-benzazepin-3-one scaffold. / de Wachter, R; de Graaf, C.; Keresztes, C; Vandormael, B; Ballet, S; Toth, G.; Rognan, D.; Tourwé, D.

In: Journal of Medicinal Chemistry, Vol. 54, 2011, p. 3384-3393.

Research output: Contribution to Journal › Article › Academic › peer-review

TY - JOUR

T1 - Synthesis, biological evaluation and automated docking of constrained analogs of the opioid peptide H-Dmt-D-AlapPhe-Gly-NH2 using the 4- or 5-metyl substsituted 4-amino-1,2,3,4-tetrahydro-2-benzazepin-3-one scaffold.

AU - de Wachter, R

AU - de Graaf, C.

AU - Keresztes, C

AU - Vandormael, B

AU - Ballet, S

AU - Toth, G.

AU - Rognan, D.

AU - Tourwé, D

PY - 2011

Y1 - 2011

M3 - Article

VL - 54

SP - 3384

EP - 3393

JO - Journal of Medicinal Chemistry

JF - Journal of Medicinal Chemistry

SN - 0022-2623

ER -