Abstract
An alkylation/olefination cascade of indolecarboxaldehydes and phosphonate-functionalized donor-acceptor cyclopropanes affords functionalized dihydrocarbazoles and cyclohepta[cd]indoles in formal (3 + 3) and (4 + 3) cycloadditions. A minor modification to the reaction conditions also allows access to the fully aromatic heterocyclic scaffolds by thermal loss of an electron-rich aryl moiety.
| Original language | English |
|---|---|
| Pages (from-to) | 7592-7596 |
| Number of pages | 5 |
| Journal | Organic letters |
| Volume | 23 |
| Issue number | 19 |
| Early online date | 20 Sept 2021 |
| DOIs | |
| Publication status | Published - 1 Oct 2021 |
Bibliographical note
Funding Information:This work was financially supported by The Netherlands Organisation for Scientific Research (NWO). We thank Elwin Janssen for NMR support and Daniël Preschel for HRMS measurements.
Publisher Copyright:
© 2021 The Authors. Published by American Chemical Society.
Funding
This work was financially supported by The Netherlands Organisation for Scientific Research (NWO). We thank Elwin Janssen for NMR support and Daniël Preschel for HRMS measurements.
