Synthesis of carboxylated flavonoids as new leads for LTD4 antagonists.

M.E. Zwaagstra; H. Timmerman; R.S. Abdoelgafoer; M.Q. Zhang

doi:10.1016/S0223-5234(97)89849-2

Synthesis of carboxylated flavonoids as new leads for LTD4 antagonists.

M.E. Zwaagstra, H. Timmerman, R.S. Abdoelgafoer, M.Q. Zhang

Medicinal chemistry

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

A series of 3'- and 5'-carboxylated chalcones, 6- or 8-carboxylated flavones and 6-carboxylated flavanones, -flavanols and -flavans were prepared. The compounds were tested for their inhibitory activities against leukotriene D

Original language	English
Pages (from-to)	861-874
Journal	European Journal of Medicinal Chemistry
Volume	31
DOIs	https://doi.org/10.1016/S0223-5234(97)89849-2
Publication status	Published - 1996

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10.1016/S0223-5234(97)89849-2

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@article{e1e4f94ed8c148d0b2b81dc91ed93cb5,

title = "Synthesis of carboxylated flavonoids as new leads for LTD4 antagonists.",

abstract = "A series of 3'- and 5'-carboxylated chalcones, 6- or 8-carboxylated flavones and 6-carboxylated flavanones, -flavanols and -flavans were prepared. The compounds were tested for their inhibitory activities against leukotriene D",

author = "M.E. Zwaagstra and H. Timmerman and R.S. Abdoelgafoer and M.Q. Zhang",

year = "1996",

doi = "10.1016/S0223-5234(97)89849-2",

language = "English",

volume = "31",

pages = "861--874",

journal = "European Journal of Medicinal Chemistry",

issn = "0223-5234",

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T1 - Synthesis of carboxylated flavonoids as new leads for LTD4 antagonists.

AU - Zwaagstra, M.E.

AU - Timmerman, H.

AU - Abdoelgafoer, R.S.

AU - Zhang, M.Q.

PY - 1996

Y1 - 1996

N2 - A series of 3'- and 5'-carboxylated chalcones, 6- or 8-carboxylated flavones and 6-carboxylated flavanones, -flavanols and -flavans were prepared. The compounds were tested for their inhibitory activities against leukotriene D

AB - A series of 3'- and 5'-carboxylated chalcones, 6- or 8-carboxylated flavones and 6-carboxylated flavanones, -flavanols and -flavans were prepared. The compounds were tested for their inhibitory activities against leukotriene D

U2 - 10.1016/S0223-5234(97)89849-2

DO - 10.1016/S0223-5234(97)89849-2

M3 - Article

SN - 0223-5234

VL - 31

SP - 861

EP - 874

JO - European Journal of Medicinal Chemistry

JF - European Journal of Medicinal Chemistry

ER -

Synthesis of carboxylated flavonoids as new leads for LTD4 antagonists.

Abstract

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