Literature concerning the value of diagnostic tests is poorly indexed in electronic bibliographical databases. - An extensive, sensitive and specific search strategy for evaluation of a diagnostic test in Medline is a combination of key words or text words concerning the diagnostic test with: 'sensitivity and specificity' (exploded), 'mass screening' (exploded), 'reference values', 'false positive reactions', 'false negative reactions', 'specificit$.tw', 'screening.tw', 'false positive$.tw', 'false negative$.tw', 'accuracy.tw', 'predictive value$.tw', 'reference value$.tw', 'roc$.tw' or 'likelihood ratio$.tw'. - Inclusion and exclusion criteria select publications which meet certain minimum requirements, such as the presence of an accepted reference standard, a clear definition of 'diseased', and the presence of a suitable outcome measure. - The methodological assessment list should contain a number of validity criteria as well as a number of criteria by which to measure the extent to which the study results can be generalised. - Important assessment criteria that may affect the diagnostic value of the test are: study design, blinding, use of different reference standards, the absence of details about the diagnostic criteria for the diagnostic test and insufficient information about the study population.
|Translated title of the contribution||Systematic reviews in practice. X. Searching, selecting and the methodological assessment of diagnostic evaluation research|
|Number of pages||4|
|Journal||Nederlands Tijdschrift voor Geneeskunde|
|Publication status||Published - 30 Nov 2002|