Targeting bacterial virulence: the coming out of type VII secretion inhibitors.

W. Bitter; C.P. Kuijl

doi:10.1016/j.chom.2014.09.010

Targeting bacterial virulence: the coming out of type VII secretion inhibitors.

W. Bitter, C.P. Kuijl

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Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

Type VII (ESX) secretion systems of pathogenic mycobacteria, such as Mycobacterium tuberculosis, are crucial for intracellular survival, host cell lysis, and the subsequent cell-to-cell spread. In this issue of Cell Host & Microbe, Rybniker et al. (2014) have used these characteristics to identify two classes of type VII secretion inhibitors.

Original language	English
Pages (from-to)	430-432
Journal	Cell host & microbe
Volume	16
Issue number	4
DOIs	https://doi.org/10.1016/j.chom.2014.09.010
Publication status	Published - 2014

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10.1016/j.chom.2014.09.010

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title = "Targeting bacterial virulence: the coming out of type VII secretion inhibitors.",

abstract = "Type VII (ESX) secretion systems of pathogenic mycobacteria, such as Mycobacterium tuberculosis, are crucial for intracellular survival, host cell lysis, and the subsequent cell-to-cell spread. In this issue of Cell Host & Microbe, Rybniker et al. (2014) have used these characteristics to identify two classes of type VII secretion inhibitors.",

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AU - Kuijl, C.P.

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AB - Type VII (ESX) secretion systems of pathogenic mycobacteria, such as Mycobacterium tuberculosis, are crucial for intracellular survival, host cell lysis, and the subsequent cell-to-cell spread. In this issue of Cell Host & Microbe, Rybniker et al. (2014) have used these characteristics to identify two classes of type VII secretion inhibitors.

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DO - 10.1016/j.chom.2014.09.010

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JO - Cell host & microbe

JF - Cell host & microbe

IS - 4

ER -

Targeting bacterial virulence: the coming out of type VII secretion inhibitors.

Abstract

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