Temporal stability of symptoms of affective disorders, cognitive vulnerability and personality over time

Sascha Y. Struijs; Femke Lamers; Mathilde G.E. Verdam; Wouter van Ballegooijen; Philip Spinhoven; Willem van der Does; Brenda W.J.H. Penninx

doi:10.1016/j.jad.2019.08.090

Temporal stability of symptoms of affective disorders, cognitive vulnerability and personality over time

Sascha Y. Struijs^*, Femke Lamers, Mathilde G.E. Verdam, Wouter van Ballegooijen, Philip Spinhoven, Willem van der Does, Brenda W.J.H. Penninx

^*Corresponding author for this work

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Abstract

Background: Signs and symptoms of psychopathology can be chronic but are generally regarded as less stable over time than markers of cognitive vulnerability and personality. Some findings suggest that these differences in temporal stability are modest in size but a rigorous examination across concepts is lacking. The current study investigated the temporal stability of affective symptoms, cognitive vulnerability markers and personality traits at various assessments over nine years. Methods: Participants of the Netherlands Study of Depression and Anxiety were assessed at baseline and reassessed after 2, 4, 6 and 9 years. They were grouped on the basis of waves of depression and anxiety CIDI-diagnoses into stable healthy (n = 768), stable patients (n = 352) and unstable patients (n = 821). We determined temporal stability by calculating intraclass correlation coefficients (ICC) and consistency indices of latent state-trait analyses (LST). Results: Temporal stability was moderate to high for symptoms (range ICC's 0.54–0.73; range consistency 0.64–0.74), cognitive vulnerability (range ICC's 0.53–0.76; range consistency 0.60–0.74) and personality (range ICC's 0.57–0.80; range consistency.60 -0.75). Consistency indices for all measures were on average a bit lower in the unstable group (ICC = 0.54) compared to the stable groups (ICC = 0.61). Overall stability was similarly high after 2, 4, 6 and 9 years. Conclusion: The 9-year stability over time of symptoms of affective disorders and that of indices of cognitive vulnerability and personality are remarkably similar and relatively high.

Original language	English
Pages (from-to)	77-83
Number of pages	7
Journal	Journal of Affective Disorders
Volume	260
Early online date	29 Aug 2019
DOIs	https://doi.org/10.1016/j.jad.2019.08.090
Publication status	Published - 1 Jan 2020

Funding

The infrastructure for the NESDA study (www.nesda.nl) is funded through the Geestkracht program of the Netherlands Organization for Health Research and Development(Zon-Mw, grant number 10-000- 1002) and is supported by participating universities and mental health care organizations (VU University Medical Center, GGZ inGeest, Arkin,Leiden University Medical Center, GGZ Rivierduinen, University Medical Center Groningen, Lentis, GGZ Friesland, GGZ Drenthe, Scientific Institute for Quality of Healthcare (IQ healthcare), Netherlands Institute for Health Services Research and Netherlands Institute of Mental Health and Addiction (Trimbos Institute). BP has received funding - not related to this work - from Jansen Research and Boehringer Ingelheim. FL has received funding from the European Union Seventh Framework Program (FP7/2007?2013) under grant agreement n? PCIG12-GA-2012-334065. None. The infrastructure for the NESDA study ( www.nesda.nl ) is funded through the Geestkracht program of the Netherlands Organization for Health Research and Development (Zon-Mw, grant number 10-000- 1002 ) and is supported by participating universities and mental health care organizations (VU University Medical Center, GGZ inGeest, Arkin,Leiden University Medical Center, GGZ Rivierduinen, University Medical Center Groningen, Lentis, GGZ Friesland, GGZ Drenthe, Scientific Institute for Quality of Healthcare (IQ healthcare), Netherlands Institute for Health Services Research and Netherlands Institute of Mental Health and Addiction (Trimbos Institute). BP has received funding - not related to this work - from Jansen Research and Boehringer Ingelheim. FL has received funding from the European Union Seventh Framework Program (FP7/2007–2013) under grant agreement n° PCIG12-GA-2012-334065 .

Funders	Funder number
Netherlands Institute for Health Services Research and Netherlands Institute of Mental Health and Addiction
Seventh Framework Programme	PCIG12-GA-2012-334065
ZonMw	10-000- 1002
Seventh Framework Programme
Leids Universitair Medisch Centrum

Keywords

Affective disorder
Anxiety disorder
Cognitive vulnerability
Depressive disorder
Personality
Temporal stability

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Temporal stability of symptoms of affective disorders cognitive vulnerability and personality over timeFinal published version, 328 KBLicence: Article 25fa Dutch Copyright Act

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title = "Temporal stability of symptoms of affective disorders, cognitive vulnerability and personality over time",

abstract = "Background: Signs and symptoms of psychopathology can be chronic but are generally regarded as less stable over time than markers of cognitive vulnerability and personality. Some findings suggest that these differences in temporal stability are modest in size but a rigorous examination across concepts is lacking. The current study investigated the temporal stability of affective symptoms, cognitive vulnerability markers and personality traits at various assessments over nine years. Methods: Participants of the Netherlands Study of Depression and Anxiety were assessed at baseline and reassessed after 2, 4, 6 and 9 years. They were grouped on the basis of waves of depression and anxiety CIDI-diagnoses into stable healthy (n = 768), stable patients (n = 352) and unstable patients (n = 821). We determined temporal stability by calculating intraclass correlation coefficients (ICC) and consistency indices of latent state-trait analyses (LST). Results: Temporal stability was moderate to high for symptoms (range ICC's 0.54–0.73; range consistency 0.64–0.74), cognitive vulnerability (range ICC's 0.53–0.76; range consistency 0.60–0.74) and personality (range ICC's 0.57–0.80; range consistency.60 -0.75). Consistency indices for all measures were on average a bit lower in the unstable group (ICC = 0.54) compared to the stable groups (ICC = 0.61). Overall stability was similarly high after 2, 4, 6 and 9 years. Conclusion: The 9-year stability over time of symptoms of affective disorders and that of indices of cognitive vulnerability and personality are remarkably similar and relatively high.",

keywords = "Affective disorder, Anxiety disorder, Cognitive vulnerability, Depressive disorder, Personality, Temporal stability",

author = "Struijs, {Sascha Y.} and Femke Lamers and Verdam, {Mathilde G.E.} and {van Ballegooijen}, Wouter and Philip Spinhoven and {van der Does}, Willem and Penninx, {Brenda W.J.H.}",

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doi = "10.1016/j.jad.2019.08.090",

language = "English",

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T1 - Temporal stability of symptoms of affective disorders, cognitive vulnerability and personality over time

AU - Struijs, Sascha Y.

AU - Lamers, Femke

AU - Verdam, Mathilde G.E.

AU - van Ballegooijen, Wouter

AU - Spinhoven, Philip

AU - van der Does, Willem

AU - Penninx, Brenda W.J.H.

PY - 2020/1/1

Y1 - 2020/1/1

N2 - Background: Signs and symptoms of psychopathology can be chronic but are generally regarded as less stable over time than markers of cognitive vulnerability and personality. Some findings suggest that these differences in temporal stability are modest in size but a rigorous examination across concepts is lacking. The current study investigated the temporal stability of affective symptoms, cognitive vulnerability markers and personality traits at various assessments over nine years. Methods: Participants of the Netherlands Study of Depression and Anxiety were assessed at baseline and reassessed after 2, 4, 6 and 9 years. They were grouped on the basis of waves of depression and anxiety CIDI-diagnoses into stable healthy (n = 768), stable patients (n = 352) and unstable patients (n = 821). We determined temporal stability by calculating intraclass correlation coefficients (ICC) and consistency indices of latent state-trait analyses (LST). Results: Temporal stability was moderate to high for symptoms (range ICC's 0.54–0.73; range consistency 0.64–0.74), cognitive vulnerability (range ICC's 0.53–0.76; range consistency 0.60–0.74) and personality (range ICC's 0.57–0.80; range consistency.60 -0.75). Consistency indices for all measures were on average a bit lower in the unstable group (ICC = 0.54) compared to the stable groups (ICC = 0.61). Overall stability was similarly high after 2, 4, 6 and 9 years. Conclusion: The 9-year stability over time of symptoms of affective disorders and that of indices of cognitive vulnerability and personality are remarkably similar and relatively high.

AB - Background: Signs and symptoms of psychopathology can be chronic but are generally regarded as less stable over time than markers of cognitive vulnerability and personality. Some findings suggest that these differences in temporal stability are modest in size but a rigorous examination across concepts is lacking. The current study investigated the temporal stability of affective symptoms, cognitive vulnerability markers and personality traits at various assessments over nine years. Methods: Participants of the Netherlands Study of Depression and Anxiety were assessed at baseline and reassessed after 2, 4, 6 and 9 years. They were grouped on the basis of waves of depression and anxiety CIDI-diagnoses into stable healthy (n = 768), stable patients (n = 352) and unstable patients (n = 821). We determined temporal stability by calculating intraclass correlation coefficients (ICC) and consistency indices of latent state-trait analyses (LST). Results: Temporal stability was moderate to high for symptoms (range ICC's 0.54–0.73; range consistency 0.64–0.74), cognitive vulnerability (range ICC's 0.53–0.76; range consistency 0.60–0.74) and personality (range ICC's 0.57–0.80; range consistency.60 -0.75). Consistency indices for all measures were on average a bit lower in the unstable group (ICC = 0.54) compared to the stable groups (ICC = 0.61). Overall stability was similarly high after 2, 4, 6 and 9 years. Conclusion: The 9-year stability over time of symptoms of affective disorders and that of indices of cognitive vulnerability and personality are remarkably similar and relatively high.

KW - Affective disorder

KW - Anxiety disorder

KW - Cognitive vulnerability

KW - Depressive disorder

KW - Personality

KW - Temporal stability

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JO - Journal of Affective Disorders

JF - Journal of Affective Disorders

ER -

Temporal stability of symptoms of affective disorders, cognitive vulnerability and personality over time

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