The Assessment of Immune Fitness

Joris C Verster; Aletta D Kraneveld; Johan Garssen

doi:10.3390/jcm12010022

The Assessment of Immune Fitness

Joris C Verster, Aletta D Kraneveld, Johan Garssen

Faculty of Science

Research output: Contribution to Journal › Review article › Academic › peer-review

Abstract

Immune fitness (i.e., adequate functioning of the immune system) is essential to maintain health, prevent and resolve disease, and improve quality of life. This article provides an overview of how to assess immune fitness. It discusses how a single-item rating scale can be used to assess immune fitness. The scale can be used in conjunction with a single "yes" or "no" question asking whether the individual is experiencing reduced immune fitness. Retrospective assessments can be complemented with the Immune Status Questionnaire (ISQ) to provide more insight into the type and frequency of experiencing specific immune-related complaints. Momentary assessments of immune fitness can be complemented with biomarker measurements in body fluids. As individuals may be unaware of systemic inflammation (e.g., biomarker concentrations outside the normal range), it remains critical to combine immune fitness assessments with biomarker measurements of immune functioning.

Original language	English
Article number	22
Journal	Journal of Clinical Medicine
Volume	12
Issue number	1
DOIs	https://doi.org/10.3390/jcm12010022
Publication status	Published - 20 Dec 2022

Funding

Over the past 3 years, J.C.V. has acted as a consultant/advisor for Eisai, KNMP, Mentis, Red Bull, Sen-Jam Pharmaceutical, and Toast! A.D.K. has held research grants from H2020, Nutricia-Danone, Netherlands Center of Translational Research, Lung Fund, SGF/Health Holland, and NWO. J.G. is a part-time employee of Nutricia Research and received research grants from Nutricia Research Foundation, Top Institute Pharma, Top Institute Food and Nutrition, GSK, STW, NWO, Friesland Campina, CCC, Raak-Pro, and EU.

Funders	Funder number
Friesland Campina
Netherlands Center of Translational Research, Lung Fund
Nutricia Research
Nutricia-Danone
Top Institute Food and Nutrition
GlaxoSmithKline
Horizon 2020 Framework Programme
Health~Holland
European Commission
Nutricia Research Foundation
Nederlandse Organisatie voor Wetenschappelijk Onderzoek
Stichting voor de Technische Wetenschappen
Top Institute Pharma
Childhood Cancer Canada
St.George Foundation

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The Assessment of Immune Fitness

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