The co-occurrence of autistic and ADHD dimensions in adults: an etiological study in 17,770 twins.

T.J.C. Polderman; R.A. Hoekstra; D. Posthuma; H. Larsson

doi:10.1038/tp.2014.84

The co-occurrence of autistic and ADHD dimensions in adults: an etiological study in 17,770 twins.

T.J.C. Polderman
, R.A. Hoekstra
, D. Posthuma
, H. Larsson

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

Autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD) often occur together. To obtain more insight in potential causes for the co-occurrence, this study examined the genetic and environmental etiology of the association between specific ASD and ADHD disorder dimensions. Self-reported data on ASD dimensions social and communication difficulties (ASDsc), and repetitive and restricted behavior and interests (ASDr), and ADHD dimensions inattention (IA), and hyperactivity/impulsivity (HI) were assessed in a community sample of 17 770 adult Swedish twins. Phenotypic, genetic and environmental associations between disorder dimensions were examined in a multivariate model, accounting for sex differences. ASDr showed the strongest associations with IA and HI in both sexes (r

Original language	English
Article number	e435
Journal	Translational Psychiatry
Volume	4
DOIs	https://doi.org/10.1038/tp.2014.84
Publication status	Published - 2014

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10.1038/tp.2014.84

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title = "The co-occurrence of autistic and ADHD dimensions in adults: an etiological study in 17,770 twins.",

abstract = "Autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD) often occur together. To obtain more insight in potential causes for the co-occurrence, this study examined the genetic and environmental etiology of the association between specific ASD and ADHD disorder dimensions. Self-reported data on ASD dimensions social and communication difficulties (ASDsc), and repetitive and restricted behavior and interests (ASDr), and ADHD dimensions inattention (IA), and hyperactivity/impulsivity (HI) were assessed in a community sample of 17 770 adult Swedish twins. Phenotypic, genetic and environmental associations between disorder dimensions were examined in a multivariate model, accounting for sex differences. ASDr showed the strongest associations with IA and HI in both sexes (r",

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AB - Autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD) often occur together. To obtain more insight in potential causes for the co-occurrence, this study examined the genetic and environmental etiology of the association between specific ASD and ADHD disorder dimensions. Self-reported data on ASD dimensions social and communication difficulties (ASDsc), and repetitive and restricted behavior and interests (ASDr), and ADHD dimensions inattention (IA), and hyperactivity/impulsivity (HI) were assessed in a community sample of 17 770 adult Swedish twins. Phenotypic, genetic and environmental associations between disorder dimensions were examined in a multivariate model, accounting for sex differences. ASDr showed the strongest associations with IA and HI in both sexes (r

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ER -

The co-occurrence of autistic and ADHD dimensions in adults: an etiological study in 17,770 twins.

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