The conserved extension of the Hbp autotransporter signal peptide does not determine targeting pathway specificity.

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

Autotransporters (ATs) of Gram-negative bacteria are often produced with an unusual signal peptide that carries a conserved N-terminal extension. Using combined in vitro and in vivo approaches we show that the extension of the AT hemoglobin protease (Hbp) does not affect targeting of Hbp via the SRP-pathway, suggesting that the extension is not involved in targeting pathway selection. © 2008 Elsevier Inc. All rights reserved.
Original languageEnglish
Pages (from-to)522-527
Number of pages6
JournalBiochemical and Biophysical Research Communications
Volume368
DOIs
Publication statusPublished - 2008

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