TY - JOUR
T1 - The dietary intake of breast cancer patients during chemotherapy
AU - Van Den Berg, M
AU - Winkels, R
AU - Dik, E
AU - De Vries, Y
AU - De Kruif, A
AU - De Vries, J
AU - Visser, M
AU - Van Laarhoven, H
AU - Kampman, E
PY - 2016
Y1 - 2016
N2 - Background: Weight gain during chemotherapy for women with breast cancer is highly prevalent. The increase in weight mainly seems to consist of increases in fat mass with loss or no change in muscle mass. These changes in body composition increase the risks of disease recurrence, cardiovascular disease and diabetes and can affect quality of life. Multiple reasons for this weight gain have been suggested, such as changes in menopausal status, changes in physical activity and changes in dietary intake. However, limited research is available regarding the dietary intake of breast cancer patients during chemotherapy. The objective of this project is to investigate whether the energy intake and macronutrient intake of breast cancer patients during chemotherapy differs from the intake of women without breast cancer. A secondary objective is to assess whether the energy intake and macronutrient intake of breast cancer patients varies over de course of a chemotherapy cycle. Materials and Methods: In this observational study, 160 patients with newly diagnosed, breast cancer (I-IIIA), scheduled for initiating (neo)adjuvant chemotherapy were recruited. 120 women without breast cancer, of the same age as the patient group (range, +/- 2 years) were recruited for the control group. To assess dietary intake, two 24 hour recalls on randomly chosen days were acquired during chemotherapy for the patients group and in a half year after baseline for the comparison group. Results: In the first 150 participants, average daily energy intake of patients was 1778+/-652 kcal compared to 1948+/-480 kcal in the control group (p > 0.005). The energy intake of breast cancer patients was lowest in the first week after chemotherapy (1668+/-808 kcal), and was higher in week 2 and 3 (1794+/-561 and 1831+/-568 kcal, respectively). However these differences were not significant. No statistically significant differences were found in the intake of macronutrients. Conclusion: Preliminary results of the first 150 participants did not show a statistically significant difference in energy and macronutrient intake between patients and the control group. No significant differences in energy intake were found during the course of a chemotherapy cycle. These preliminary results suggest that energy and macronutrient intake does not account for the often reported increase in weight in breast cancer patients. As this study is currently ongoing, updated numbers will be presented during the conference.
AB - Background: Weight gain during chemotherapy for women with breast cancer is highly prevalent. The increase in weight mainly seems to consist of increases in fat mass with loss or no change in muscle mass. These changes in body composition increase the risks of disease recurrence, cardiovascular disease and diabetes and can affect quality of life. Multiple reasons for this weight gain have been suggested, such as changes in menopausal status, changes in physical activity and changes in dietary intake. However, limited research is available regarding the dietary intake of breast cancer patients during chemotherapy. The objective of this project is to investigate whether the energy intake and macronutrient intake of breast cancer patients during chemotherapy differs from the intake of women without breast cancer. A secondary objective is to assess whether the energy intake and macronutrient intake of breast cancer patients varies over de course of a chemotherapy cycle. Materials and Methods: In this observational study, 160 patients with newly diagnosed, breast cancer (I-IIIA), scheduled for initiating (neo)adjuvant chemotherapy were recruited. 120 women without breast cancer, of the same age as the patient group (range, +/- 2 years) were recruited for the control group. To assess dietary intake, two 24 hour recalls on randomly chosen days were acquired during chemotherapy for the patients group and in a half year after baseline for the comparison group. Results: In the first 150 participants, average daily energy intake of patients was 1778+/-652 kcal compared to 1948+/-480 kcal in the control group (p > 0.005). The energy intake of breast cancer patients was lowest in the first week after chemotherapy (1668+/-808 kcal), and was higher in week 2 and 3 (1794+/-561 and 1831+/-568 kcal, respectively). However these differences were not significant. No statistically significant differences were found in the intake of macronutrients. Conclusion: Preliminary results of the first 150 participants did not show a statistically significant difference in energy and macronutrient intake between patients and the control group. No significant differences in energy intake were found during the course of a chemotherapy cycle. These preliminary results suggest that energy and macronutrient intake does not account for the often reported increase in weight in breast cancer patients. As this study is currently ongoing, updated numbers will be presented during the conference.
M3 - Article
SN - 0959-8049
VL - 57
SP - S27
JO - European Journal of Cancer
JF - European Journal of Cancer
ER -