The effect of a tooth/tongue gel and mouthwash regimen on morning oral malodour: A 3-week single-blind randomized clinical trial

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Abstract

Aim: To compare the effects of a regimen consisting of a tooth/tongue gel, tongue cleaner and mouthwash with the effects of using standard fluoride dentifrice on the organoleptic oral malodour score (ORG) and volatile sulphur compounds (VSCs).
Materials and methods: A total, 66 non-dental students participated in a 3-week parallel, single-blind, randomized, controlled clinical trial. The test group used a tongue cleaner, a tooth/tongue gel and mouthwash containing amine fluoride/stannous fluoride and zinc lactate as oral malodour counteractive. The control group used a standard fluoride dentifrice. Measurements were taken in the morning at baseline, at days 1, 7 and 21. The primary outcome was the ORG score. The secondary outcome, the VSC measurement, was assessed using OralChroma™ (H2S, CH3SH, (CH3)2S) and Halimeter®. Tongue coating thickness and tongue discoloration were scored. At baseline and day 21, the participants' self-perceptions were assessed.
Results: At day 1 for the ORG, H2S, CH3SH and Halimeter®readings, a significant decrease was observed in the test group. At day 21, the decrease in H2S and the Halimeter®outcomes were maintained for the test group, and a significant increase in tongue surface discoloration was observed. The test group evaluated their "morning breath upon awakening" as significantly better (P=.001) after 21 days.
Conclusion: A significant overnight effect on morning oral malodour was observed for most of the parameters in favour of the test group. At day 21, the effect of prolonged use was significant for H2S and the Halimeter®readings, although not for the primary ORG outcome parameter.
Original languageEnglish
Pages (from-to)92-102
JournalInternational Journal of Dental Hygiene
Volume16
Issue number1
DOIs
Publication statusPublished - 2018

Funding

Funding information The study was performed with a commission from ACTA Dental Research BV. ACTA Research BV received financial support from GABA for its commitment to award this project to the Department of Periodontology of ACTA The Department of Periodontology received products from GABA International. The test group used Meridol® Halitosis tooth and tongue gel, a Meridol® Halitosis tongue cleaner, and Meridol® Halitosis mouthwash, and a Meridol® Halitosis manual toothbrush. The control group used a Meridol® manual toothbrush. Currently, GABA International is part of the Colgate-Palmolive Company. The authors gratefully acknowledge the second judge Sam Supranoto, who helped to conduct the study and who was responsible for operating the Halimeter® and OralChroma™ apparatuses. In addition, Esther Martin and Danielle Ekkelboom are acknowledged for their help during the clinical study. The study was performed with a commission from ACTA Dental Research BV. ACTA Research BV received financial support from GABA for its commitment to award this project to the Department of Periodontology of ACTA

FundersFunder number
ACTA Dental Research BV
Department of Periodontology of ACTA
GABA
Colgate-Palmolive Company
GABA International

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