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The effect of photodynamic therapy on postoperative pain in teeth with primary endodontic infection

  • Esdras Gabriel Alves-Silva
  • , Rodrigo Arruda-Vasconcelos
  • , Lidiane Mendes Louzada
  • , Adriana de-Jesus-Soares
  • , Caio Cezar Randi Ferraz
  • , José Flávio Affonso Almeida
  • , Marina Angélica Marciano
  • , Carolina Steiner-Oliveira
  • , Marina Stella Bello-Silva
  • , Hagay Shemesh
  • , Brenda Paula Figueiredo de Almeida Gomes*
  • *Corresponding author for this work

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

Introduction: : The objective of this study was to investigate the action of photodynamic therapy on pain control after endodontic treatment in asymptomatic teeth with a primary infection, within a single visit. Methods: : Sixty (60) single-rooted teeth with pulp necrosis and periapical lesions were selected and randomly divided into two (2) groups (n = 30), according to the protocol; a control group (CG) and a group using photodynamic therapy (aPDT). The canals were instrumented with Reciproc files # 25 up to 40 along the entire length of the canal, using 2% chlorhexidine gel as the auxiliary chemical substance, followed by irrigation with sterile saline. aPDT consited of 0.005% methylene blue as photosensitizer, using AsGaAl diode laser, 660 nm wavelength, 100 mW of power and 9 J of energy, using optical fibers with 365 μm in diameter. The canals were filled with Endomethasone N cement. Results: : Pain intensity was assessed at 8, 12, 24, 48, 72 h and 1 week after endodontic treatment using a visual analogue scale. The level of pain was classified as none (0), mild (1–3), moderate (4–7) or severe (8–10). The data were at a significance level of 5%. There was a statistically significant difference (p<0.05) in the periods of 8, 12, 24, 48 and 72 h between the control group and the aPDT group. After 1 week, there was no statistically significant difference. Conclusions: : It is concluded that photodynamic therapy had a significant effect on decreasing post-endodontic treatment pain in teeth with necrotic pulp and asymptomatic periapical lesions.

Original languageEnglish
Article number102700
Pages (from-to)1-7
Number of pages7
JournalPhotodiagnosis and Photodynamic Therapy
Volume37
Early online date23 Dec 2021
DOIs
Publication statusPublished - Mar 2022

Bibliographical note

Funding Information:
This work was supported by the São Paulo State Research Support Foundation (FAPESP, 2015/23479-5, 2017/25242-8, 2019/10755-5, 2019/19300-0, 2019/09115-1), National Council for Scientific and Technological Development (CNPQ 303852/2019-4 ; 164905/2020-0 ) and Coordination for the Improvement of Level Personnel Superior (CAPES, Finance Code 001). The authors deny any conflict of interest.

Funding Information:
This work was supported by the S?o Paulo State Research Support Foundation (FAPESP, 2015/23479-5, 2017/25242-8, 2019/10755-5, 2019/19300-0, 2019/09115-1), National Council for Scientific and Technological Development (CNPQ 303852/2019-4; 164905/2020-0) and Coordination for the Improvement of Level Personnel Superior (CAPES, Finance Code 001). The authors deny any conflict of interest.

Publisher Copyright:
© 2021

Funding

This work was supported by the São Paulo State Research Support Foundation (FAPESP, 2015/23479-5, 2017/25242-8, 2019/10755-5, 2019/19300-0, 2019/09115-1), National Council for Scientific and Technological Development (CNPQ 303852/2019-4 ; 164905/2020-0 ) and Coordination for the Improvement of Level Personnel Superior (CAPES, Finance Code 001). The authors deny any conflict of interest. This work was supported by the S?o Paulo State Research Support Foundation (FAPESP, 2015/23479-5, 2017/25242-8, 2019/10755-5, 2019/19300-0, 2019/09115-1), National Council for Scientific and Technological Development (CNPQ 303852/2019-4; 164905/2020-0) and Coordination for the Improvement of Level Personnel Superior (CAPES, Finance Code 001). The authors deny any conflict of interest.

Keywords

  • Endodontics
  • Laser
  • Photodynamic therapy
  • Postoperative pain
  • Primary endodontic infection

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