TY - JOUR
T1 - The effects of partial sleep deprivation on energy balance
T2 - A systematic review and meta-analysis
AU - Al Khatib, H. K.
AU - Harding, S. V.
AU - Darzi, J.
AU - Pot, G. K.
PY - 2017/5/1
Y1 - 2017/5/1
N2 - Background/Objectives:It is unknown whether short sleep duration causatively contributes to weight gain. Studies investigating effects of partial sleep deprivation (PSD) on energy balance components report conflicting findings. Our objective was to conduct a systematic review and meta-analysis of human intervention studies assessing the effects of PSD on energy intake (EI) and energy expenditure (EE).Subjects/Methods:EMBASE, Medline, Cochrane CENTRAL, Web of Science and Scopus were searched. Differences in EI and total EE following PSD compared with a control condition were generated using the inverse variance method with random-effects models. Secondary outcomes included macronutrient distribution and resting metabolic rate. Heterogeneity was quantified with the I 2 -statistic.Results:Seventeen studies (n=496) were eligible for inclusion in the systematic review, and 11 studies (n=172) provided sufficient data to be included in meta-analyses. EI was significantly increased by 385 kcal (95% confidence interval: 252, 517; P<0.00001) following PSD compared with the control condition. We found no significant change in total EE or resting metabolic rate as a result of PSD. The observed increase in EI was accompanied by significantly higher fat and lower protein intakes, but no effect on carbohydrate intake.Conclusions:The pooled effects of the studies with extractable data indicated that PSD resulted in increased EI with no effect on EE, leading to a net positive energy balance, which in the long term may contribute to weight gain.
AB - Background/Objectives:It is unknown whether short sleep duration causatively contributes to weight gain. Studies investigating effects of partial sleep deprivation (PSD) on energy balance components report conflicting findings. Our objective was to conduct a systematic review and meta-analysis of human intervention studies assessing the effects of PSD on energy intake (EI) and energy expenditure (EE).Subjects/Methods:EMBASE, Medline, Cochrane CENTRAL, Web of Science and Scopus were searched. Differences in EI and total EE following PSD compared with a control condition were generated using the inverse variance method with random-effects models. Secondary outcomes included macronutrient distribution and resting metabolic rate. Heterogeneity was quantified with the I 2 -statistic.Results:Seventeen studies (n=496) were eligible for inclusion in the systematic review, and 11 studies (n=172) provided sufficient data to be included in meta-analyses. EI was significantly increased by 385 kcal (95% confidence interval: 252, 517; P<0.00001) following PSD compared with the control condition. We found no significant change in total EE or resting metabolic rate as a result of PSD. The observed increase in EI was accompanied by significantly higher fat and lower protein intakes, but no effect on carbohydrate intake.Conclusions:The pooled effects of the studies with extractable data indicated that PSD resulted in increased EI with no effect on EE, leading to a net positive energy balance, which in the long term may contribute to weight gain.
UR - http://www.scopus.com/inward/record.url?scp=84994078549&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84994078549&partnerID=8YFLogxK
U2 - 10.1038/ejcn.2016.201
DO - 10.1038/ejcn.2016.201
M3 - Review article
AN - SCOPUS:84994078549
SN - 0954-3007
VL - 71
SP - 614
EP - 624
JO - European Journal of Clinical Nutrition
JF - European Journal of Clinical Nutrition
IS - 5
ER -
