The EPDS-Lifetime: assessment of lifetime prevalence and risk factors for perinatal depression in a large cohort of depressed women

Samantha Meltzer-Brody, Lynn Boschloo, Ian Jones, Patrick F Sullivan, Brenda W Penninx

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

Perinatal depression (PND) is a common complication of pregnancy and postpartum associated with significant morbidity. We had three goals: (1) to explore the performance of a new lifetime version of the Edinburgh Postnatal Depression Scale (EPDS-Lifetime) to assess lifetime prevalence of PND; (2) to assess prevalence of lifetime PND in women with prior histories of major depressive episode (MDE); and (3) to evaluate risk factors for PND. Subjects were from the Netherlands Study of Depression and Anxiety (NESDA). The EPDS was modified by adding lifetime PND screening questions, assessing worst episode, and symptom timing of onset. Of 682 women with lifetime MDD and a live birth, 276 (40.4 %) had a positive EPDS score of ≥12 consistent with PND. Women with PND more often sought professional help (p < 0.001) and received treatment (p = 0.001). Independent risk indicators for PND included younger age, higher education, high neuroticism, childhood trauma, and sexual abuse. We found that two in five parous women with a history of MDD had lifetime PND and that the PND episodes were more severe than MDD occurring outside of the perinatal period. The EPDS-Lifetime shows promise as a tool for assessing lifetime histories of PND in clinical and research settings.

Original languageEnglish
Pages (from-to)465-473
Number of pages9
JournalArchives of womens mental health
Volume16
Issue number6
Early online date1 Aug 2013
DOIs
Publication statusPublished - Dec 2013

Fingerprint

Depression
Postpartum Depression
Pregnancy Complications
Sex Offenses
Live Birth
Netherlands
Postpartum Period
Anxiety
Morbidity
Education
Wounds and Injuries
Research

Keywords

  • Adult
  • Depression/diagnosis
  • Depressive Disorder, Major/diagnosis
  • Female
  • Humans
  • Mass Screening/methods
  • Maternal Behavior
  • Mothers/psychology
  • Netherlands/epidemiology
  • Perinatal Care
  • Pregnancy
  • Pregnancy Complications/epidemiology
  • Prevalence
  • Reproducibility of Results
  • Risk Assessment
  • Risk Factors
  • Surveys and Questionnaires
  • Young Adult

Cite this

Meltzer-Brody, Samantha ; Boschloo, Lynn ; Jones, Ian ; Sullivan, Patrick F ; Penninx, Brenda W. / The EPDS-Lifetime : assessment of lifetime prevalence and risk factors for perinatal depression in a large cohort of depressed women. In: Archives of womens mental health. 2013 ; Vol. 16, No. 6. pp. 465-473.
@article{27e3e46860384740bd9b6df58c609a90,
title = "The EPDS-Lifetime: assessment of lifetime prevalence and risk factors for perinatal depression in a large cohort of depressed women",
abstract = "Perinatal depression (PND) is a common complication of pregnancy and postpartum associated with significant morbidity. We had three goals: (1) to explore the performance of a new lifetime version of the Edinburgh Postnatal Depression Scale (EPDS-Lifetime) to assess lifetime prevalence of PND; (2) to assess prevalence of lifetime PND in women with prior histories of major depressive episode (MDE); and (3) to evaluate risk factors for PND. Subjects were from the Netherlands Study of Depression and Anxiety (NESDA). The EPDS was modified by adding lifetime PND screening questions, assessing worst episode, and symptom timing of onset. Of 682 women with lifetime MDD and a live birth, 276 (40.4 {\%}) had a positive EPDS score of ≥12 consistent with PND. Women with PND more often sought professional help (p < 0.001) and received treatment (p = 0.001). Independent risk indicators for PND included younger age, higher education, high neuroticism, childhood trauma, and sexual abuse. We found that two in five parous women with a history of MDD had lifetime PND and that the PND episodes were more severe than MDD occurring outside of the perinatal period. The EPDS-Lifetime shows promise as a tool for assessing lifetime histories of PND in clinical and research settings.",
keywords = "Adult, Depression/diagnosis, Depressive Disorder, Major/diagnosis, Female, Humans, Mass Screening/methods, Maternal Behavior, Mothers/psychology, Netherlands/epidemiology, Perinatal Care, Pregnancy, Pregnancy Complications/epidemiology, Prevalence, Reproducibility of Results, Risk Assessment, Risk Factors, Surveys and Questionnaires, Young Adult",
author = "Samantha Meltzer-Brody and Lynn Boschloo and Ian Jones and Sullivan, {Patrick F} and Penninx, {Brenda W}",
year = "2013",
month = "12",
doi = "10.1007/s00737-013-0372-9",
language = "English",
volume = "16",
pages = "465--473",
journal = "Archives of womens mental health",
issn = "1434-1816",
publisher = "Springer Wien",
number = "6",

}

The EPDS-Lifetime : assessment of lifetime prevalence and risk factors for perinatal depression in a large cohort of depressed women. / Meltzer-Brody, Samantha; Boschloo, Lynn; Jones, Ian; Sullivan, Patrick F; Penninx, Brenda W.

In: Archives of womens mental health, Vol. 16, No. 6, 12.2013, p. 465-473.

Research output: Contribution to JournalArticleAcademicpeer-review

TY - JOUR

T1 - The EPDS-Lifetime

T2 - assessment of lifetime prevalence and risk factors for perinatal depression in a large cohort of depressed women

AU - Meltzer-Brody, Samantha

AU - Boschloo, Lynn

AU - Jones, Ian

AU - Sullivan, Patrick F

AU - Penninx, Brenda W

PY - 2013/12

Y1 - 2013/12

N2 - Perinatal depression (PND) is a common complication of pregnancy and postpartum associated with significant morbidity. We had three goals: (1) to explore the performance of a new lifetime version of the Edinburgh Postnatal Depression Scale (EPDS-Lifetime) to assess lifetime prevalence of PND; (2) to assess prevalence of lifetime PND in women with prior histories of major depressive episode (MDE); and (3) to evaluate risk factors for PND. Subjects were from the Netherlands Study of Depression and Anxiety (NESDA). The EPDS was modified by adding lifetime PND screening questions, assessing worst episode, and symptom timing of onset. Of 682 women with lifetime MDD and a live birth, 276 (40.4 %) had a positive EPDS score of ≥12 consistent with PND. Women with PND more often sought professional help (p < 0.001) and received treatment (p = 0.001). Independent risk indicators for PND included younger age, higher education, high neuroticism, childhood trauma, and sexual abuse. We found that two in five parous women with a history of MDD had lifetime PND and that the PND episodes were more severe than MDD occurring outside of the perinatal period. The EPDS-Lifetime shows promise as a tool for assessing lifetime histories of PND in clinical and research settings.

AB - Perinatal depression (PND) is a common complication of pregnancy and postpartum associated with significant morbidity. We had three goals: (1) to explore the performance of a new lifetime version of the Edinburgh Postnatal Depression Scale (EPDS-Lifetime) to assess lifetime prevalence of PND; (2) to assess prevalence of lifetime PND in women with prior histories of major depressive episode (MDE); and (3) to evaluate risk factors for PND. Subjects were from the Netherlands Study of Depression and Anxiety (NESDA). The EPDS was modified by adding lifetime PND screening questions, assessing worst episode, and symptom timing of onset. Of 682 women with lifetime MDD and a live birth, 276 (40.4 %) had a positive EPDS score of ≥12 consistent with PND. Women with PND more often sought professional help (p < 0.001) and received treatment (p = 0.001). Independent risk indicators for PND included younger age, higher education, high neuroticism, childhood trauma, and sexual abuse. We found that two in five parous women with a history of MDD had lifetime PND and that the PND episodes were more severe than MDD occurring outside of the perinatal period. The EPDS-Lifetime shows promise as a tool for assessing lifetime histories of PND in clinical and research settings.

KW - Adult

KW - Depression/diagnosis

KW - Depressive Disorder, Major/diagnosis

KW - Female

KW - Humans

KW - Mass Screening/methods

KW - Maternal Behavior

KW - Mothers/psychology

KW - Netherlands/epidemiology

KW - Perinatal Care

KW - Pregnancy

KW - Pregnancy Complications/epidemiology

KW - Prevalence

KW - Reproducibility of Results

KW - Risk Assessment

KW - Risk Factors

KW - Surveys and Questionnaires

KW - Young Adult

U2 - 10.1007/s00737-013-0372-9

DO - 10.1007/s00737-013-0372-9

M3 - Article

VL - 16

SP - 465

EP - 473

JO - Archives of womens mental health

JF - Archives of womens mental health

SN - 1434-1816

IS - 6

ER -