Abstract
Insertion of additional octarepeats into the prion protein gene has been genetically linked to familial Creutzfeldt Jakob disease and hence to de novo generation of infectious prions. The pivotal event during prion formation is the conversion of the normal prion protein (PrP
| Original language | English |
|---|---|
| Pages (from-to) | 3268-3275 |
| Journal | Journal of Biological Chemistry |
| Volume | 281 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 2006 |
Bibliographical note
The expanded octarepeat domain selectively binds prions and disrupts homomeric prion protein interactionsUN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
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