Abstract
The nature and degree of objective sleep impairments in insomnia disorder remain unclear. This issue is complicated further by potential changes in sleep architecture on the first compared with subsequent nights in the laboratory. Evidence regarding differential first-night effects in people with insomnia disorder and controls is mixed. Here, we aimed to further characterize insomnia- and night-related differences in sleep architecture. A comprehensive set of 26 sleep variables was derived from two consecutive nights of polysomnography in 61 age-matched patients with insomnia and 61 good sleeper controls. People with insomnia expressed consistently poorer sleep than controls on several variables during both nights. While poorer sleep during the first night was observed in both groups, there were qualitative differences regarding the specific sleep variables expressing a first-night effect. Short sleep (total sleep time < 6 hr) was more likely during the first night and in insomnia, although approximately 40% of patients with insomnia presenting with short sleep on night 1 no longer met this criterion on night 2, which is important given the notion of short-sleeping insomnia as a robust subtype.
| Original language | English |
|---|---|
| Article number | e13897 |
| Pages (from-to) | 1-6 |
| Number of pages | 6 |
| Journal | Journal of Sleep Research |
| Volume | 33 |
| Issue number | 1 |
| Early online date | 5 Apr 2023 |
| DOIs | |
| Publication status | Published - Feb 2024 |
Bibliographical note
Funding Information:This work was facilitated by funding from the European Research Council (projects ERC‐ADG‐2014‐671084 INSOMNIA, ERC‐ADG‐2020‐957641 INSOMNIA AID, and ERC‐ADG‐2021‐101055383 OVERNIGHT). The authors wish to thank the following individuals for their assistance in data collection: Bahar Adibi Rafsani, Jeroen Benjamins, Tom Bresser, Jessica Bruyel, Michele Colombo, Michelle De Haan, Kim Dekker, Laura Dekker, Jessica Foster‐Dingley, Katerina Georgopoulou, Brit Giesbertz, German Herrero Gomez, Simon Houtman, Vincent Huson, Savannah Ikelaar, Oti Lakbila‐Kamal, Jeanne Leerssen, Arjan Miedema, Katerina Nikolakopoulou, Joyce Reesen, Verena Sommer, Diederick Stoffers, Yvon Sweere, Bart Te Lindert, Sjors Van de Ven, Glenn Van der Lande, Wisse Van der Meijden, Ysbrand Van der Werf, Floor Van Oosterhout, Frank Van Schalkwijk, Inger Van Steenoven, Lina Vandermeulen, Marije Vermeulen, Josien Visser, Yishul Wei.
Funding Information:
This work was facilitated by funding from the European Research Council (projects ERC-ADG-2014-671084 INSOMNIA, ERC-ADG-2020-957641 INSOMNIA AID, and ERC-ADG-2021-101055383 OVERNIGHT). The authors wish to thank the following individuals for their assistance in data collection: Bahar Adibi Rafsani, Jeroen Benjamins, Tom Bresser, Jessica Bruyel, Michele Colombo, Michelle De Haan, Kim Dekker, Laura Dekker, Jessica Foster-Dingley, Katerina Georgopoulou, Brit Giesbertz, German Herrero Gomez, Simon Houtman, Vincent Huson, Savannah Ikelaar, Oti Lakbila-Kamal, Jeanne Leerssen, Arjan Miedema, Katerina Nikolakopoulou, Joyce Reesen, Verena Sommer, Diederick Stoffers, Yvon Sweere, Bart Te Lindert, Sjors Van de Ven, Glenn Van der Lande, Wisse Van der Meijden, Ysbrand Van der Werf, Floor Van Oosterhout, Frank Van Schalkwijk, Inger Van Steenoven, Lina Vandermeulen, Marije Vermeulen, Josien Visser, Yishul Wei.
Publisher Copyright:
© 2023 The Authors. Journal of Sleep Research published by John Wiley & Sons Ltd on behalf of European Sleep Research Society.
Keywords
- electroencephalogram
- first-night effect
- insomnia
- polysomnography
- sleep architecture