Using data from the Berlin diary study (N = 1223), we examined associations between the General Factor of Personality (GFP) and daily social experiences, self-esteem, and mood (positive and negative affect). As predicted, high-(vs. low) GFP individuals reported fewer daily interpersonal conflicts, better relationship quality, and better impressions on others. Also, relationship quality and daily impressions both mediated the relation between the GFP and mood and self-esteem. Multilevel analyses showed that, compared to low-GFP participants, high-GFP participants seemed less disturbed when experiencing conflict. In sum, the results were in line with the notion of the GFP as social effectiveness, with important consequences for people's daily social life and well-being.