The genetic analysis of repeated measures I. Simplex models

D.I. Boomsma, P.C.M. Molenaar

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The well-known simplex model is extended to a model that may be used for the genetic and environmental analysis of covariance structures. This "double" simplex structure can be specified as a LISREL model. It is shown that data which give rise to a simplex correlation structure, such as repeated-measures data, do not fit a factor-analysis model. The parameter estimation of the simplex model is illustrated with computer-simulated twin data. © 1987 Plenum Publishing Corporation.
Original languageEnglish
Pages (from-to)111-123
JournalBehavior Genetics
Issue number2
Publication statusPublished - 1987

Cohort Studies

  • Netherlands Twin Register (NTR)


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