The genetic architecture of body mass index from infancy to adulthood modified by parental education

K. Silventoinen; C. Huppertz; C.E.M. van Beijsterveldt; M. Bartels; G. Willemsen; D.I. Boomsma

doi:10.1002/oby.21588

The genetic architecture of body mass index from infancy to adulthood modified by parental education

K. Silventoinen, C. Huppertz, C.E.M. van Beijsterveldt, M. Bartels, G. Willemsen, D.I. Boomsma

Biological Psychology

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

Objective: A higher prevalence of obesity in lower socioeconomic classes is common in Western societies. This study examined the role of gene–environment interactions in the association between parental education and body mass index (BMI) from infancy to the onset of adulthood. Methods: Parentally reported BMI from 1 to 13 and self-reported BMI from 14 to 20 years of age were collected in 16,646 complete Dutch twin pairs and analyzed by genetic twin modeling. Results: At 7 to 8 years of age, children whose parents had middle or low educational levels had more excess weight than the children of more highly educated parents, and the difference increased until 18 to 20 years of age. The major part of the BMI variation was explained by additive genetic factors (a

Original language	English
Pages (from-to)	2004-2011
Journal	Obesity
Volume	24
Issue number	9
DOIs	https://doi.org/10.1002/oby.21588
Publication status	Published - 2016

Cohort Studies

Netherlands Twin Register (NTR)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1002/oby.21588

Persistent URL (handle)

Persistent link

Cite this

@article{bfcb3241fc0443aeb147fdbff02f4a59,

title = "The genetic architecture of body mass index from infancy to adulthood modified by parental education",

abstract = "Objective: A higher prevalence of obesity in lower socioeconomic classes is common in Western societies. This study examined the role of gene–environment interactions in the association between parental education and body mass index (BMI) from infancy to the onset of adulthood. Methods: Parentally reported BMI from 1 to 13 and self-reported BMI from 14 to 20 years of age were collected in 16,646 complete Dutch twin pairs and analyzed by genetic twin modeling. Results: At 7 to 8 years of age, children whose parents had middle or low educational levels had more excess weight than the children of more highly educated parents, and the difference increased until 18 to 20 years of age. The major part of the BMI variation was explained by additive genetic factors (a",

author = "K. Silventoinen and C. Huppertz and {van Beijsterveldt}, C.E.M. and M. Bartels and G. Willemsen and D.I. Boomsma",

year = "2016",

doi = "10.1002/oby.21588",

language = "English",

volume = "24",

pages = "2004--2011",

journal = "Obesity",

issn = "1930-7381",

publisher = "John Wiley and Sons Inc.",

number = "9",

}

TY - JOUR

T1 - The genetic architecture of body mass index from infancy to adulthood modified by parental education

AU - Silventoinen, K.

AU - Huppertz, C.

AU - van Beijsterveldt, C.E.M.

AU - Bartels, M.

AU - Willemsen, G.

AU - Boomsma, D.I.

PY - 2016

Y1 - 2016

N2 - Objective: A higher prevalence of obesity in lower socioeconomic classes is common in Western societies. This study examined the role of gene–environment interactions in the association between parental education and body mass index (BMI) from infancy to the onset of adulthood. Methods: Parentally reported BMI from 1 to 13 and self-reported BMI from 14 to 20 years of age were collected in 16,646 complete Dutch twin pairs and analyzed by genetic twin modeling. Results: At 7 to 8 years of age, children whose parents had middle or low educational levels had more excess weight than the children of more highly educated parents, and the difference increased until 18 to 20 years of age. The major part of the BMI variation was explained by additive genetic factors (a

AB - Objective: A higher prevalence of obesity in lower socioeconomic classes is common in Western societies. This study examined the role of gene–environment interactions in the association between parental education and body mass index (BMI) from infancy to the onset of adulthood. Methods: Parentally reported BMI from 1 to 13 and self-reported BMI from 14 to 20 years of age were collected in 16,646 complete Dutch twin pairs and analyzed by genetic twin modeling. Results: At 7 to 8 years of age, children whose parents had middle or low educational levels had more excess weight than the children of more highly educated parents, and the difference increased until 18 to 20 years of age. The major part of the BMI variation was explained by additive genetic factors (a

U2 - 10.1002/oby.21588

DO - 10.1002/oby.21588

M3 - Article

SN - 1930-7381

VL - 24

SP - 2004

EP - 2011

JO - Obesity

JF - Obesity

IS - 9

ER -

The genetic architecture of body mass index from infancy to adulthood modified by parental education

Abstract

Cohort Studies

UN SDGs

Access to Document

Persistent URL (handle)

Fingerprint

Cite this