The impact of childhood abuse and recent stress on serum brain-derived neurotrophic factor and the moderating role of BDNF Val(66)Met

B.M. Elzinga, M.L. Molendijk, R.C.O. Voshaar, B.A.A. Bus, J. Prickaerts, P. Spinhoven, B.W.J.H. Penninx

    Research output: Contribution to JournalArticleAcademicpeer-review

    189 Downloads (Pure)

    Abstract

    Rationale: Recent findings show lowered brain-derived neurotrophic factor (BDNF) levels in major depressive disorder (MDD). Exposure to stressful life events may (partly) underlie these BDNF reductions, but little is known about the effects of early or recent life stress on BDNF levels. Moreover, the effects of stressful events on BDNF levels may in part be conditional upon a common variant on the BDNF gene (Val
    Original languageEnglish
    Pages (from-to)319-328
    JournalPsychopharmacology
    Volume214
    Issue number1
    DOIs
    Publication statusPublished - 2011

    Fingerprint

    Dive into the research topics of 'The impact of childhood abuse and recent stress on serum brain-derived neurotrophic factor and the moderating role of BDNF Val(66)Met'. Together they form a unique fingerprint.

    Cite this