The influence of a hydrogen peroxide and glycerol containing mouthrinse on plaque accumulation: a 3-day non-brushing model

N.L. Hoenderdos; N.A. Rosema; D.E. Slot; M.F. Timmerman; U. van der Velden; G.A. van der Weijden

doi:10.1111/j.1601-5037.2009.00367.x

The influence of a hydrogen peroxide and glycerol containing mouthrinse on plaque accumulation: a 3-day non-brushing model

Research output: Contribution to Journal › Article › Academic

Abstract

Aim: To evaluate the inhibition of plaque growth by an experimental mouthrinse (BioXyl®) based on hydrogen peroxide/glycerol.

Design: It was a double-blind, randomized study involving 40 volunteers in good general health. At the start of the trial, all participants received a dental prophylaxis to remove all plaque deposits. During the next 3 days subjects refrained from any mechanical oral hygiene procedure, except for the allocated mouthrinse being either the hydrogen peroxide (H2O2; 0.013% H2O2/0.004% glycerol) or the placebo without H2O2. At the third day of appointment, plaque levels were assessed at six sites per tooth.

Results: The test group had a mean overall plaque score of 2.66 and the placebo group of 2.70. The difference in plaque scores between the two groups was not statistically significant.

Conclusions: The results of this pilot study showed that there was no statistically significant difference between the H2O2/glycerol group and the placebo group with respect to plaque inhibition within this study design.

Original language	Undefined/Unknown
Pages (from-to)	294-298
Journal	International Journal of Dental Hygiene
Volume	7
Issue number	4
DOIs	https://doi.org/10.1111/j.1601-5037.2009.00367.x
Publication status	Published - 2009

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@article{d27950189f7243aba7c12667c7a01e54,

title = "The influence of a hydrogen peroxide and glycerol containing mouthrinse on plaque accumulation: a 3-day non-brushing model",

abstract = "Aim: To evaluate the inhibition of plaque growth by an experimental mouthrinse (BioXyl{\textregistered}) based on hydrogen peroxide/glycerol. Design: It was a double-blind, randomized study involving 40 volunteers in good general health. At the start of the trial, all participants received a dental prophylaxis to remove all plaque deposits. During the next 3 days subjects refrained from any mechanical oral hygiene procedure, except for the allocated mouthrinse being either the hydrogen peroxide (H2O2; 0.013\% H2O2/0.004\% glycerol) or the placebo without H2O2. At the third day of appointment, plaque levels were assessed at six sites per tooth. Results: The test group had a mean overall plaque score of 2.66 and the placebo group of 2.70. The difference in plaque scores between the two groups was not statistically significant. Conclusions: The results of this pilot study showed that there was no statistically significant difference between the H2O2/glycerol group and the placebo group with respect to plaque inhibition within this study design. ",

author = "N.L. Hoenderdos and N.A. Rosema and D.E. Slot and M.F. Timmerman and \{van der Velden\}, U. and \{van der Weijden\}, G.A.",

year = "2009",

doi = "10.1111/j.1601-5037.2009.00367.x",

language = "Undefined/Unknown",

volume = "7",

pages = "294--298",

journal = "International Journal of Dental Hygiene",

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T1 - The influence of a hydrogen peroxide and glycerol containing mouthrinse on plaque accumulation: a 3-day non-brushing model

AU - Hoenderdos, N.L.

AU - Rosema, N.A.

AU - Slot, D.E.

AU - Timmerman, M.F.

AU - van der Velden, U.

AU - van der Weijden, G.A.

PY - 2009

Y1 - 2009

N2 - Aim: To evaluate the inhibition of plaque growth by an experimental mouthrinse (BioXyl®) based on hydrogen peroxide/glycerol. Design: It was a double-blind, randomized study involving 40 volunteers in good general health. At the start of the trial, all participants received a dental prophylaxis to remove all plaque deposits. During the next 3 days subjects refrained from any mechanical oral hygiene procedure, except for the allocated mouthrinse being either the hydrogen peroxide (H2O2; 0.013% H2O2/0.004% glycerol) or the placebo without H2O2. At the third day of appointment, plaque levels were assessed at six sites per tooth. Results: The test group had a mean overall plaque score of 2.66 and the placebo group of 2.70. The difference in plaque scores between the two groups was not statistically significant. Conclusions: The results of this pilot study showed that there was no statistically significant difference between the H2O2/glycerol group and the placebo group with respect to plaque inhibition within this study design.

AB - Aim: To evaluate the inhibition of plaque growth by an experimental mouthrinse (BioXyl®) based on hydrogen peroxide/glycerol. Design: It was a double-blind, randomized study involving 40 volunteers in good general health. At the start of the trial, all participants received a dental prophylaxis to remove all plaque deposits. During the next 3 days subjects refrained from any mechanical oral hygiene procedure, except for the allocated mouthrinse being either the hydrogen peroxide (H2O2; 0.013% H2O2/0.004% glycerol) or the placebo without H2O2. At the third day of appointment, plaque levels were assessed at six sites per tooth. Results: The test group had a mean overall plaque score of 2.66 and the placebo group of 2.70. The difference in plaque scores between the two groups was not statistically significant. Conclusions: The results of this pilot study showed that there was no statistically significant difference between the H2O2/glycerol group and the placebo group with respect to plaque inhibition within this study design.

U2 - 10.1111/j.1601-5037.2009.00367.x

DO - 10.1111/j.1601-5037.2009.00367.x

M3 - Article

SN - 1601-5029

VL - 7

SP - 294

EP - 298

JO - International Journal of Dental Hygiene

JF - International Journal of Dental Hygiene

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