The influence of co-morbidity on health-related quality of life in asthma and COPD patients

H. A H Wijnhoven*, D.M.W. Kriegsman, A.E. Hesselink, M. de Haan, F.G. Schellevis

*Corresponding author for this work

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

This study examines the association between somatic co-morbidity and both general and disease-specific health-related quality of life (HRQoL) in patients with asthma and chronic obstructive pulmonary disease (COPD). A cross-sectional analysis was done among 161 COPD patients and 395 asthma patients, aged 40-75 years, recruited from general practice. In the total study population, 47% had no, 32% had one, and 21% had two or more somatic co-morbid conditions, with no significant differences between asthma and COPD patients. Co-morbidity appeared to be associated with poor disease-specific HRQoL in asthma [odds ratio (OR) = 2.08 (1.37-3.18)] and with poor general HRQoL in asthma [OR = 2.96 (1.93-4.53)] and COPD [1.81 (0.91-3.60)] patients. Poorest HRQoL was found in patients with more than one co-morbid condition. Cardiac disease and hypertension were associated with poor disease-specific HRQoL in asthma. Of all co-morbid conditions, musculoskeletal disorders were most strongly associated with poor general HRQoL. Cardiac disease was found to be associated with general and disease-specific HRQoL in asthma but not in COPD. In studies on patients with asthma or COPD aged 40-75 years, co-morbidity should be treated as a determinant of HRQoL.

Original languageEnglish
Pages (from-to)468-475
Number of pages8
JournalRespiratory Medicine
Volume97
Issue number5
DOIs
Publication statusPublished - 1 May 2003

Keywords

  • Asthma
  • Comorbidity
  • COPD
  • Lung diseases
  • Obstructive
  • Quality of life

Fingerprint

Dive into the research topics of 'The influence of co-morbidity on health-related quality of life in asthma and COPD patients'. Together they form a unique fingerprint.

Cite this