The joint impact of family history of myocardial infarction and other risk factors on 12-year coronary heart disease mortality

J M Boer, E.J. Feskens, W M Monique Verschuren, J C Seidell, D. Kromhout

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

We investigated the impact of family history of myocardial infarction on 12-year coronary heart disease mortality. Men and women with a family history had an increased risk for coronary heart disease death, irrespective of other risk factors (RR = 1.58; 95% CI = 1.17-2.13 and RR = 2.12; 95% CI = 1.11-4.05, respectively). Women with a family history seemed to be more susceptible to the detrimental effects of smoking; not to the effects of other risk factors. We found no effect modification by family history in men.

Original languageEnglish
Pages (from-to)767-770
Number of pages4
JournalEpidemiology
Volume10
Issue number6
DOIs
Publication statusPublished - Nov 1999

Keywords

  • Adult
  • Body Weight
  • Coronary Disease
  • Female
  • Humans
  • Life Style
  • Male
  • Middle Aged
  • Myocardial Infarction
  • Netherlands
  • Risk Factors
  • Smoking
  • Journal Article
  • Research Support, Non-U.S. Gov't

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