The Ligand-Receptor-G-Protein Ternary Complex as a GTP-Synthase. Steady-state Proton Pumping and Dose-Response relationships for eta Adrenoceptors

K.J. Broadley; P.H.J. Nederkoorn; H. Timmerman; D. Timms; R.H. Davies

doi:10.1006/jtbi.2000.2067

The Ligand-Receptor-G-Protein Ternary Complex as a GTP-Synthase. Steady-state Proton Pumping and Dose-Response relationships for eta Adrenoceptors

K.J. Broadley, P.H.J. Nederkoorn, H. Timmerman, D. Timms, R.H. Davies

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

Steady-state solutions are developed for the rate of Gα.GTP production in a synthase model of the ligand-receptor-G-protein ternary complex activated by a ligand-receptor proton pumping mechanism. The effective rate, k

Original language	English
Pages (from-to)	297-320
Journal	Journal of Theoretical Biology
Volume	205
DOIs	https://doi.org/10.1006/jtbi.2000.2067
Publication status	Published - 2000

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10.1006/jtbi.2000.2067

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title = "The Ligand-Receptor-G-Protein Ternary Complex as a GTP-Synthase. Steady-state Proton Pumping and Dose-Response relationships for eta Adrenoceptors",

abstract = "Steady-state solutions are developed for the rate of Gα.GTP production in a synthase model of the ligand-receptor-G-protein ternary complex activated by a ligand-receptor proton pumping mechanism. The effective rate, k",

author = "K.J. Broadley and P.H.J. Nederkoorn and H. Timmerman and D. Timms and R.H. Davies",

year = "2000",

doi = "10.1006/jtbi.2000.2067",

language = "English",

volume = "205",

pages = "297--320",

journal = "Journal of Theoretical Biology",

issn = "0022-5193",

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T1 - The Ligand-Receptor-G-Protein Ternary Complex as a GTP-Synthase. Steady-state Proton Pumping and Dose-Response relationships for eta Adrenoceptors

AU - Broadley, K.J.

AU - Nederkoorn, P.H.J.

AU - Timmerman, H.

AU - Timms, D.

AU - Davies, R.H.

PY - 2000

Y1 - 2000

N2 - Steady-state solutions are developed for the rate of Gα.GTP production in a synthase model of the ligand-receptor-G-protein ternary complex activated by a ligand-receptor proton pumping mechanism. The effective rate, k

AB - Steady-state solutions are developed for the rate of Gα.GTP production in a synthase model of the ligand-receptor-G-protein ternary complex activated by a ligand-receptor proton pumping mechanism. The effective rate, k

U2 - 10.1006/jtbi.2000.2067

DO - 10.1006/jtbi.2000.2067

M3 - Article

SN - 0022-5193

VL - 205

SP - 297

EP - 320

JO - Journal of Theoretical Biology

JF - Journal of Theoretical Biology

ER -

The Ligand-Receptor-G-Protein Ternary Complex as a GTP-Synthase. Steady-state Proton Pumping and Dose-Response relationships for eta Adrenoceptors

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