The Ligand-Receptor-G-Protein Ternary Complex as a GTP-Synthase. Steady-state Proton Pumping and Dose-Response relationships for eta Adrenoceptors

K.J. Broadley, P.H.J. Nederkoorn, H. Timmerman, D. Timms, R.H. Davies

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

Steady-state solutions are developed for the rate of Gα.GTP production in a synthase model of the ligand-receptor-G-protein ternary complex activated by a ligand-receptor proton pumping mechanism. The effective rate, k
Original languageEnglish
Pages (from-to)297-320
JournalJournal of Theoretical Biology
Volume205
DOIs
Publication statusPublished - 2000

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