The link between periodontitis and erectile dysfunction (vasculogenic impotence).

PERIODONTITIS HAS BEEN ASSOCIATED with atherosclerotic cardiovascular diseases (ACVD). Based on longitudinal studies in large cohorts it has been shown that periodontitis can be regarded as another risk factor for the sequalae of ACVD such as myocardial infarction, cerebrovascular accidents and death. Atherosclerotic pathology lays at the basis of ACVD events and periodontitis can exacerbate at the atherogenic process. With this knowledge, it seems highly conceivable that periodontitis is also associated with erectile dysfunction (ED; vasculogenic importence). Currently ED is mainly considered as another complication of atherosclerotic changes in the vascular system. Nine studies have investigated the relationship of ED with periodontitis and all found an association. One meta-analysis, including 4 eligible (out total of 9) studies reported a significant odds ratio (OR) of 3 [95% confidence interval (CI) 1.87 - 5.05, p <0.001] for the association. However, there was considerable heterogeneity among the 4 studies. Moreover, one short-term treatment study indicated that periodontal intervention can decrease ED complaints as measured by questionnaires. These preliminary positive results can also be included in the motivation of dental professionals and male patients; periodontitis screening and, if indicated, periodontal treatment, seems helpful to manage this form of impotence.