The neuro-immune axis: Prospect for novel treatments for mental disorders

A.D. Kraneveld; C.G.M. de Theije; F. van Heesch; Y. Borre; S. de Kivit; B. Olivier; M. Korte; J. Garssen

doi:10.1111/bcpt.12154

The neuro-immune axis: Prospect for novel treatments for mental disorders

A.D. Kraneveld, C.G.M. de Theije, F. van Heesch, Y. Borre, S. de Kivit, B. Olivier, M. Korte, J. Garssen

Research output: Contribution to Journal › Review article › Academic › peer-review

Abstract

Disturbed bidirectional pathways between the (central) nervous system and immune system have been implicated in various mental disorders, including depressive and neurodevelopmental disorders. In this minireview, the role of the neuro-immune axis and its targetability in relation to major depression and autism spectrum disorder will be discussed. All together, the management of these and possibly other multi-factorial mental disorders needs a new and integrated therapeutic approach. Pharmacologically bioactive molecules as well as medical nutrition targeting the (gut)-immune-brain axis could be such an approach. © 2013 Nordic Pharmacological Society.

Original language	English
Pages (from-to)	128-136
Journal	Basic and Clinical Pharmacology and Toxicology
Volume	114
Issue number	1
DOIs	https://doi.org/10.1111/bcpt.12154
Publication status	Published - Jan 2014
Externally published	Yes

Access to Document

10.1111/bcpt.12154

Persistent URL (handle)

Persistent link

Cite this

@article{e4c7ff12c4384d19a2298fb38c331adb,

title = "The neuro-immune axis: Prospect for novel treatments for mental disorders",

abstract = "Disturbed bidirectional pathways between the (central) nervous system and immune system have been implicated in various mental disorders, including depressive and neurodevelopmental disorders. In this minireview, the role of the neuro-immune axis and its targetability in relation to major depression and autism spectrum disorder will be discussed. All together, the management of these and possibly other multi-factorial mental disorders needs a new and integrated therapeutic approach. Pharmacologically bioactive molecules as well as medical nutrition targeting the (gut)-immune-brain axis could be such an approach. {\textcopyright} 2013 Nordic Pharmacological Society.",

author = "A.D. Kraneveld and \{de Theije\}, C.G.M. and \{van Heesch\}, F. and Y. Borre and \{de Kivit\}, S. and B. Olivier and M. Korte and J. Garssen",

year = "2014",

month = jan,

doi = "10.1111/bcpt.12154",

language = "English",

volume = "114",

pages = "128--136",

journal = "Basic and Clinical Pharmacology and Toxicology",

issn = "1742-7835",

publisher = "Wiley-Blackwell",

number = "1",

}

TY - JOUR

T1 - The neuro-immune axis

T2 - Prospect for novel treatments for mental disorders

AU - Kraneveld, A.D.

AU - de Theije, C.G.M.

AU - van Heesch, F.

AU - Borre, Y.

AU - de Kivit, S.

AU - Olivier, B.

AU - Korte, M.

AU - Garssen, J.

PY - 2014/1

Y1 - 2014/1

N2 - Disturbed bidirectional pathways between the (central) nervous system and immune system have been implicated in various mental disorders, including depressive and neurodevelopmental disorders. In this minireview, the role of the neuro-immune axis and its targetability in relation to major depression and autism spectrum disorder will be discussed. All together, the management of these and possibly other multi-factorial mental disorders needs a new and integrated therapeutic approach. Pharmacologically bioactive molecules as well as medical nutrition targeting the (gut)-immune-brain axis could be such an approach. © 2013 Nordic Pharmacological Society.

AB - Disturbed bidirectional pathways between the (central) nervous system and immune system have been implicated in various mental disorders, including depressive and neurodevelopmental disorders. In this minireview, the role of the neuro-immune axis and its targetability in relation to major depression and autism spectrum disorder will be discussed. All together, the management of these and possibly other multi-factorial mental disorders needs a new and integrated therapeutic approach. Pharmacologically bioactive molecules as well as medical nutrition targeting the (gut)-immune-brain axis could be such an approach. © 2013 Nordic Pharmacological Society.

UR - https://www.scopus.com/pages/publications/84890863959

UR - https://www.scopus.com/inward/citedby.url?scp=84890863959&partnerID=8YFLogxK

U2 - 10.1111/bcpt.12154

DO - 10.1111/bcpt.12154

M3 - Review article

SN - 1742-7835

VL - 114

SP - 128

EP - 136

JO - Basic and Clinical Pharmacology and Toxicology

JF - Basic and Clinical Pharmacology and Toxicology

IS - 1

ER -

The neuro-immune axis: Prospect for novel treatments for mental disorders

Abstract

Access to Document

Persistent URL (handle)

Other files and links

Fingerprint

Cite this