The Prevalence of Cortical Gray Matter Atrophy May Be Overestimated in the Healthy Aging Brain (Reply to Fjell et al. (2010) and Raz and Lindenberger (2010)

Burgmans et al. (2009) stated that the prevalence of cortical gray matter atrophy may be overestimated in the healthy aging brain, because the inclusion of participants with preclinical cognitive pathology might have been responsible for the age effects found in previous studies. Fjell et al. (2010) and Raz and Lindenberger (2010) verified this statement by reanalyzing previously published data. They both argue that it is unlikely that preclinical cognitive pathology explains cortical gray matter atrophy in healthy aging. Burgmans et al. (2010) respond to these commentaries. © 2010 American Psychological Association.