The role of 5-HT(1A) receptors in learning and memory

S.O. Ogren, T.M. Eriksson, E. Elvander-Tottie, C. D'Addario, J.C. Ekström, P. Svenningsson, B. Meister, J. Kehr, O. Stiedl

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

The ascending serotonin (5-HT) neurons innervate the cerebral cortex, hippocampus, septum and amygdala, all representing brain regions associated with various domains of cognition. The 5-HT innervation is diffuse and extensively arborized with few synaptic contacts, which indicates that 5-HT can affect a large number of neurons in a paracrine mode. Serotonin signaling is mediated by 14 receptor subtypes with different functional and transductional properties. The 5-HT
Original languageEnglish
Pages (from-to)54-77
JournalBehavioural Brain Research
Volume195
DOIs
Publication statusPublished - 2008

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