TY - JOUR
T1 - The role of double dissociation studies in the search for candidate endophenotypes for the comorbidity of attention deficit hyperactivity disorder and reading disability.
AU - de Jong, C.G.W.
AU - Oosterlaan, J.
AU - Sergeant, J.A.
PY - 2006
Y1 - 2006
N2 - The neuropsychological underpinnings of Attention Deficit Hyperactivity Disorder (ADHD) and Reading Disability (RD) and their comorbidity may be studied usefully with the double dissociation design. The results of studies using the double dissociation method may be linked to the search for an endophenotype of ADHD and RD and their comorbidity. This endophenotype may eventually shed more light on the genetic origins of both ADHD and RD and their comorbidity. Executive functioning appears to be a candidate endophenotype of the comorbidity of ADHD and RD. Future studies, it is argued, should combine both the double dissociation design with the Additive Factor Method in this endeavour. Additionally, more attention needs to be given to the subtypes of ADHD, RD, and their association with Dyscalculia to determine useful endophenotype(s).
AB - The neuropsychological underpinnings of Attention Deficit Hyperactivity Disorder (ADHD) and Reading Disability (RD) and their comorbidity may be studied usefully with the double dissociation design. The results of studies using the double dissociation method may be linked to the search for an endophenotype of ADHD and RD and their comorbidity. This endophenotype may eventually shed more light on the genetic origins of both ADHD and RD and their comorbidity. Executive functioning appears to be a candidate endophenotype of the comorbidity of ADHD and RD. Future studies, it is argued, should combine both the double dissociation design with the Additive Factor Method in this endeavour. Additionally, more attention needs to be given to the subtypes of ADHD, RD, and their association with Dyscalculia to determine useful endophenotype(s).
U2 - 10.1080/10349120600716158
DO - 10.1080/10349120600716158
M3 - Article
SN - 1034-912X
VL - 53
SP - 177
EP - 193
JO - International Journal of Disability, Development and Education
JF - International Journal of Disability, Development and Education
IS - 2
ER -