The role of double dissociation studies in the search for candidate endophenotypes for the comorbidity of attention deficit hyperactivity disorder and reading disability.

C.G.W. de Jong, J. Oosterlaan, J.A. Sergeant

Research output: Contribution to JournalArticleAcademicpeer-review

247 Downloads (Pure)

Abstract

The neuropsychological underpinnings of Attention Deficit Hyperactivity Disorder (ADHD) and Reading Disability (RD) and their comorbidity may be studied usefully with the double dissociation design. The results of studies using the double dissociation method may be linked to the search for an endophenotype of ADHD and RD and their comorbidity. This endophenotype may eventually shed more light on the genetic origins of both ADHD and RD and their comorbidity. Executive functioning appears to be a candidate endophenotype of the comorbidity of ADHD and RD. Future studies, it is argued, should combine both the double dissociation design with the Additive Factor Method in this endeavour. Additionally, more attention needs to be given to the subtypes of ADHD, RD, and their association with Dyscalculia to determine useful endophenotype(s).
Original languageEnglish
Pages (from-to)177-193
Number of pages18
JournalInternational Journal of Disability, Development and Education
Volume53
Issue number2
DOIs
Publication statusPublished - 2006

Fingerprint

Dive into the research topics of 'The role of double dissociation studies in the search for candidate endophenotypes for the comorbidity of attention deficit hyperactivity disorder and reading disability.'. Together they form a unique fingerprint.

Cite this