The unusual kinetics of lactate dehydrogenase of Schistosoma mansoni and their role in the rapid metabolic switch after penetration of the mammalian host

Michiel L. Bexkens; Olivier M.F. Martin; Jos M. van den Heuvel; Marion G.J. Schmitz; Bas Teusink; Barbara M. Bakker; Jaap J. van Hellemond; Jurgen R. Haanstra; Malcolm D. Walkinshaw; Aloysius G.M. Tielens

doi:10.1016/j.ijpara.2024.03.005

The unusual kinetics of lactate dehydrogenase of Schistosoma mansoni and their role in the rapid metabolic switch after penetration of the mammalian host

Michiel L. Bexkens, Olivier M.F. Martin, Jos M. van den Heuvel, Marion G.J. Schmitz, Bas Teusink, Barbara M. Bakker, Jaap J. van Hellemond, Jurgen R. Haanstra, Malcolm D. Walkinshaw, Aloysius G.M. Tielens

Research output: Contribution to Journal › Article › Academic › peer-review

Original language	Undefined/Unknown
Pages (from-to)	367-378
Journal	International Journal for Parasitology
Volume	54
Issue number	7
DOIs	https://doi.org/10.1016/j.ijpara.2024.03.005
Publication status	Published - Mar 2024

Funding

We thank Josan Yauw (VU Amsterdam) for her work on the initial versions of the model and Brett Olivier for valuable comments on the model description. The investigations were supported by the Netherlands Foundation for Chemical Research (SON) with financial aid from the Netherlands Organization for Scientific Research (NWO).

Funders	Funder number
Netherlands Foundation for Chemical Research
Neotropical Ornithological Society
Nederlandse Organisatie voor Wetenschappelijk Onderzoek

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10.1016/j.ijpara.2024.03.005

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Bexkens, M. L., Martin, O. M. F., Heuvel, J. M. V. D., Schmitz, M. G. J., Teusink, B., Bakker, B. M., Hellemond, J. J. V., Haanstra, J. R., Walkinshaw, M. D., & Tielens, A. G. M. (2024). The unusual kinetics of lactate dehydrogenase of Schistosoma mansoni and their role in the rapid metabolic switch after penetration of the mammalian host. International Journal for Parasitology, 54(7), 367-378. https://doi.org/10.1016/j.ijpara.2024.03.005

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title = "The unusual kinetics of lactate dehydrogenase of Schistosoma mansoni and their role in the rapid metabolic switch after penetration of the mammalian host",

author = "Bexkens, {Michiel L.} and Martin, {Olivier M.F.} and Heuvel, {Jos M. van den} and Schmitz, {Marion G.J.} and Bas Teusink and Bakker, {Barbara M.} and Hellemond, {Jaap J. van} and Haanstra, {Jurgen R.} and Walkinshaw, {Malcolm D.} and Tielens, {Aloysius G.M.}",

year = "2024",

month = mar,

doi = "10.1016/j.ijpara.2024.03.005",

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volume = "54",

pages = "367--378",

journal = "International Journal for Parasitology",

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Bexkens, ML, Martin, OMF, Heuvel, JMVD, Schmitz, MGJ, Teusink, B , Bakker, BM, Hellemond, JJV, Haanstra, JR, Walkinshaw, MD & Tielens, AGM 2024, 'The unusual kinetics of lactate dehydrogenase of Schistosoma mansoni and their role in the rapid metabolic switch after penetration of the mammalian host', International Journal for Parasitology, vol. 54, no. 7, pp. 367-378. https://doi.org/10.1016/j.ijpara.2024.03.005

The unusual kinetics of lactate dehydrogenase of Schistosoma mansoni and their role in the rapid metabolic switch after penetration of the mammalian host. / Bexkens, Michiel L.; Martin, Olivier M.F.; Heuvel, Jos M. van den et al.
In: International Journal for Parasitology, Vol. 54, No. 7, 03.2024, p. 367-378.

Research output: Contribution to Journal › Article › Academic › peer-review

TY - JOUR

T1 - The unusual kinetics of lactate dehydrogenase of Schistosoma mansoni and their role in the rapid metabolic switch after penetration of the mammalian host

AU - Bexkens, Michiel L.

AU - Martin, Olivier M.F.

AU - Heuvel, Jos M. van den

AU - Schmitz, Marion G.J.

AU - Teusink, Bas

AU - Bakker, Barbara M.

AU - Hellemond, Jaap J. van

AU - Haanstra, Jurgen R.

AU - Walkinshaw, Malcolm D.

AU - Tielens, Aloysius G.M.

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M3 - Article

SN - 0020-7519

VL - 54

SP - 367

EP - 378

JO - International Journal for Parasitology

JF - International Journal for Parasitology

IS - 7

ER -

The unusual kinetics of lactate dehydrogenase of Schistosoma mansoni and their role in the rapid metabolic switch after penetration of the mammalian host

Funding

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