TY - JOUR
T1 - The use of autogenous bone mixed with a biphasic calcium phosphate in a maxillary sinus floor elevation procedure with a 6-month healing time
T2 - A clinical, radiological, histological and histomorphometric evaluation
AU - Bouwman, W.F.
AU - Bravenboer, N.
AU - ten Bruggenkate, C.M.
AU - Schulten, E.A.J.M.
PY - 2020/5/1
Y1 - 2020/5/1
N2 - Background: In this study it is evaluated whether autogenous bone mixed with biphasic calcium phosphate (BCP) used in a maxillary sinus floor elevation (MSFE) leads to improved bone formation. Materials and methods: In five patients a unilateral MSFE was performed. Histological and histomorphometric analyses were performed on bone biopsies that were obtained 6 months after MSFE during dental implant surgery. Results: The average vital bone volume was 29.9% of the total biopsy (BV/TV, SD±10.1) of which 7.1% was osteoid (OV/BV, SD ± 4.8). The osteoid surface (OS/BS) covered 26.0% (SD ± 13.4) of the bone surface. The BS/TV covered 4.7 mm2/mm3 (SD 2.3). Compared with previous studies the analyses showed a difference for trabecular thickness (Tb. Th.) and osteoid surface (OS/BS), but not for BV/TV, OV/BV and the number of osteoclasts. Conclusion: MSFE with autogenous bone mixed with BCP shows an amount of newly formed bone that is comparable with the findings from the previously published 6-month study with pure BCP. However, a better distribution of the new bone over the entire biopsy was observed.
AB - Background: In this study it is evaluated whether autogenous bone mixed with biphasic calcium phosphate (BCP) used in a maxillary sinus floor elevation (MSFE) leads to improved bone formation. Materials and methods: In five patients a unilateral MSFE was performed. Histological and histomorphometric analyses were performed on bone biopsies that were obtained 6 months after MSFE during dental implant surgery. Results: The average vital bone volume was 29.9% of the total biopsy (BV/TV, SD±10.1) of which 7.1% was osteoid (OV/BV, SD ± 4.8). The osteoid surface (OS/BS) covered 26.0% (SD ± 13.4) of the bone surface. The BS/TV covered 4.7 mm2/mm3 (SD 2.3). Compared with previous studies the analyses showed a difference for trabecular thickness (Tb. Th.) and osteoid surface (OS/BS), but not for BV/TV, OV/BV and the number of osteoclasts. Conclusion: MSFE with autogenous bone mixed with BCP shows an amount of newly formed bone that is comparable with the findings from the previously published 6-month study with pure BCP. However, a better distribution of the new bone over the entire biopsy was observed.
U2 - 10.3390/COATINGS10050462
DO - 10.3390/COATINGS10050462
M3 - Article
SN - 2079-6412
VL - 10
JO - Coatings
JF - Coatings
IS - 5
M1 - 462
ER -