TY - JOUR
T1 - Time course of arterial vascular adaptations to inactivity and paralyses in humans
AU - de Groot, P.C.E.
AU - van Kuppevelt, D.
AU - Pons, C.
AU - van der Woude, L.H.V.
AU - Hopman, M.T.E.
PY - 2003
Y1 - 2003
N2 - Purpose: The aim of the present study was to assess the time course of vascular adaptations to inactivity and paralyses in humans. The spinal cord-injured (SCI) population offers a unique "human model of nature" to assess peripheral vascular adaptations and its time course to extreme inactivity and paralyses. Methods: Arterial diameters and red blood cell velocity of the carotid artery (CA), common femoral artery (FA), and brachial artery (BA) were measured using echo Doppler ultrasound. Fifteen SCI persons with lesions varying from 6 wk to 13 months postinjury participated in a cross-sectional study (SCI-CS), 6 SCI individuals were included for longitudinal measurements (SCI-L) at weeks 6, 8, 12, 16, 20, and 24 after the trauma, and 16 able-bodied individuals served as a control group (C). Results: Within 6 wk after the SCI, diameter (SCI-CS: 0.68 ± 0.09 cm, SCI-L: 0.67 ± 0.04 cm, C: 0.95 ± 0.07 cm) and blood flow (SCI-CS: 299 ± 112 mL·min
AB - Purpose: The aim of the present study was to assess the time course of vascular adaptations to inactivity and paralyses in humans. The spinal cord-injured (SCI) population offers a unique "human model of nature" to assess peripheral vascular adaptations and its time course to extreme inactivity and paralyses. Methods: Arterial diameters and red blood cell velocity of the carotid artery (CA), common femoral artery (FA), and brachial artery (BA) were measured using echo Doppler ultrasound. Fifteen SCI persons with lesions varying from 6 wk to 13 months postinjury participated in a cross-sectional study (SCI-CS), 6 SCI individuals were included for longitudinal measurements (SCI-L) at weeks 6, 8, 12, 16, 20, and 24 after the trauma, and 16 able-bodied individuals served as a control group (C). Results: Within 6 wk after the SCI, diameter (SCI-CS: 0.68 ± 0.09 cm, SCI-L: 0.67 ± 0.04 cm, C: 0.95 ± 0.07 cm) and blood flow (SCI-CS: 299 ± 112 mL·min
U2 - 10.1249/01.MSS.0000099088.21547.67
DO - 10.1249/01.MSS.0000099088.21547.67
M3 - Article
SN - 0195-9131
VL - 35
SP - 1997
EP - 1985
JO - Medicine and Science in Sports and Exercise
JF - Medicine and Science in Sports and Exercise
IS - 12
ER -
