Tomosyn-2 is required for normal motor performance in mice and sustains neurotransmission at motor endplates.

C.J. Geerts; J.J. Plomp; B. Koopmans; M. Loos; EM van der Pijl; M.A. van der Valk; M. Verhage; A.J.A. Groffen

doi:10.1007/s00429-014-0766-0

Tomosyn-2 is required for normal motor performance in mice and sustains neurotransmission at motor endplates.

C.J. Geerts, J.J. Plomp, B. Koopmans, M. Loos, EM van der Pijl, M.A. van der Valk, M. Verhage, A.J.A. Groffen

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

Tomosyn-1 (STXBP5) is a soluble NSF attachment protein receptor complex-binding protein that inhibits vesicle fusion, but the role of tomosyn-2 (STXBP5L) in the mammalian nervous system is still unclear. Here we generated tomosyn-2 null (Tom2

Original language	English
Pages (from-to)	1971-1982
Journal	Brain Structure and Function
Volume	220
Issue number	4
DOIs	https://doi.org/10.1007/s00429-014-0766-0
Publication status	Published - 2015

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10.1007/s00429-014-0766-0

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title = "Tomosyn-2 is required for normal motor performance in mice and sustains neurotransmission at motor endplates.",

abstract = "Tomosyn-1 (STXBP5) is a soluble NSF attachment protein receptor complex-binding protein that inhibits vesicle fusion, but the role of tomosyn-2 (STXBP5L) in the mammalian nervous system is still unclear. Here we generated tomosyn-2 null (Tom2",

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T1 - Tomosyn-2 is required for normal motor performance in mice and sustains neurotransmission at motor endplates.

AU - Geerts, C.J.

AU - Plomp, J.J.

AU - Koopmans, B.

AU - Loos, M.

AU - van der Pijl, EM

AU - van der Valk, M.A.

AU - Verhage, M.

AU - Groffen, A.J.A.

PY - 2015

Y1 - 2015

N2 - Tomosyn-1 (STXBP5) is a soluble NSF attachment protein receptor complex-binding protein that inhibits vesicle fusion, but the role of tomosyn-2 (STXBP5L) in the mammalian nervous system is still unclear. Here we generated tomosyn-2 null (Tom2

AB - Tomosyn-1 (STXBP5) is a soluble NSF attachment protein receptor complex-binding protein that inhibits vesicle fusion, but the role of tomosyn-2 (STXBP5L) in the mammalian nervous system is still unclear. Here we generated tomosyn-2 null (Tom2

U2 - 10.1007/s00429-014-0766-0

DO - 10.1007/s00429-014-0766-0

M3 - Article

SN - 1863-2653

VL - 220

SP - 1971

EP - 1982

JO - Brain Structure and Function

JF - Brain Structure and Function

IS - 4

ER -

Tomosyn-2 is required for normal motor performance in mice and sustains neurotransmission at motor endplates.

Abstract

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