Total Synthesis of Aspidosperma and Strychnos Alkaloids through Indole Dearomatization

Jordy M. Saya, Eelco Ruijter*, Romano V.A. Orru

*Corresponding author for this work

Research output: Contribution to JournalReview articleAcademicpeer-review

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Abstract

Monoterpenoid indole alkaloids are the major class of tryptamine-derived alkaloids found in nature. Together with their structural complexity, this has attracted great interest from synthetic organic chemists. In this Review, the syntheses of Aspidosperma and Strychnos alkaloids through dearomatization of indoles are discussed.

Original languageEnglish
Pages (from-to)8916-8935
Number of pages20
JournalChemistry - A European Journal
Volume25
Issue number38
Early online date17 Apr 2019
DOIs
Publication statusPublished - 5 Jul 2019

Keywords

  • alkaloids
  • biomimetic synthesis
  • dearomatization
  • indoles
  • natural product synthesis

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