Abstract
Monoterpenoid indole alkaloids are the major class of tryptamine-derived alkaloids found in nature. Together with their structural complexity, this has attracted great interest from synthetic organic chemists. In this Review, the syntheses of Aspidosperma and Strychnos alkaloids through dearomatization of indoles are discussed.
| Original language | English |
|---|---|
| Pages (from-to) | 8916-8935 |
| Number of pages | 20 |
| Journal | Chemistry - A European Journal |
| Volume | 25 |
| Issue number | 38 |
| Early online date | 17 Apr 2019 |
| DOIs | |
| Publication status | Published - 5 Jul 2019 |
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Keywords
- alkaloids
- biomimetic synthesis
- dearomatization
- indoles
- natural product synthesis
Cite this
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Total Synthesis of Aspidosperma and Strychnos Alkaloids through Indole Dearomatization. / Saya, Jordy M.; Ruijter, Eelco; Orru, Romano V.A.
In: Chemistry - A European Journal, Vol. 25, No. 38, 05.07.2019, p. 8916-8935.Research output: Contribution to Journal › Review article › Academic › peer-review
TY - JOUR
T1 - Total Synthesis of Aspidosperma and Strychnos Alkaloids through Indole Dearomatization
AU - Saya, Jordy M.
AU - Ruijter, Eelco
AU - Orru, Romano V.A.
PY - 2019/7/5
Y1 - 2019/7/5
N2 - Monoterpenoid indole alkaloids are the major class of tryptamine-derived alkaloids found in nature. Together with their structural complexity, this has attracted great interest from synthetic organic chemists. In this Review, the syntheses of Aspidosperma and Strychnos alkaloids through dearomatization of indoles are discussed.
AB - Monoterpenoid indole alkaloids are the major class of tryptamine-derived alkaloids found in nature. Together with their structural complexity, this has attracted great interest from synthetic organic chemists. In this Review, the syntheses of Aspidosperma and Strychnos alkaloids through dearomatization of indoles are discussed.
KW - alkaloids
KW - biomimetic synthesis
KW - dearomatization
KW - indoles
KW - natural product synthesis
UR - http://www.scopus.com/inward/record.url?scp=85066049953&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85066049953&partnerID=8YFLogxK
U2 - 10.1002/chem.201901130
DO - 10.1002/chem.201901130
M3 - Review article
VL - 25
SP - 8916
EP - 8935
JO - Chemistry: A European Journal
JF - Chemistry: A European Journal
SN - 0947-6539
IS - 38
ER -