Total Synthesis of Aspidosperma and Strychnos Alkaloids through Indole Dearomatization

Research output: Contribution to JournalReview articleAcademicpeer-review

Abstract

Monoterpenoid indole alkaloids are the major class of tryptamine-derived alkaloids found in nature. Together with their structural complexity, this has attracted great interest from synthetic organic chemists. In this Review, the syntheses of Aspidosperma and Strychnos alkaloids through dearomatization of indoles are discussed.

Original languageEnglish
JournalChemistry - A European Journal
DOIs
Publication statusPublished - 1 Jan 2019

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Alkaloids
Secologanin Tryptamine Alkaloids
Indoles
indole
tryptamine

Keywords

  • alkaloids
  • biomimetic synthesis
  • dearomatization
  • indoles
  • natural product synthesis

Cite this

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abstract = "Monoterpenoid indole alkaloids are the major class of tryptamine-derived alkaloids found in nature. Together with their structural complexity, this has attracted great interest from synthetic organic chemists. In this Review, the syntheses of Aspidosperma and Strychnos alkaloids through dearomatization of indoles are discussed.",
keywords = "alkaloids, biomimetic synthesis, dearomatization, indoles, natural product synthesis",
author = "Saya, {Jordy M.} and Eelco Ruijter and Orru, {Romano V.A.}",
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