Toxicokinetics and bioconcentration of polycyclic aromatic hydrocarbons in freshwater isopods

A.G.M. van Hattum; J.F. Cid Montañés

doi:10.1021/es9800479

Toxicokinetics and bioconcentration of polycyclic aromatic hydrocarbons in freshwater isopods

A.G.M. van Hattum
, J.F. Cid Montañés

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Abstract

A novel method based on a first-order two-compartment model was used to determine the bioconcentration and toxicokinetic rate constants of six different polycyclic aromatic hydrocarbons (PAHs) in the freshwater isopod Asellus aquaticus, a common species in most European freshwater systems. Numerical integration and iterative parameter estimation techniques were applied to account for time-varying aqueous exposure concentrations. All PAHs exhibited a rapid uptake. Monophasic elimination patterns were observed for benzo[e]pyrene and benzo[a]-pyrene (biological half-life t

Original language	English
Pages (from-to)	2409-2417
Journal	Environmental Science and Technology
Volume	33
DOIs	https://doi.org/10.1021/es9800479
Publication status	Published - 1999

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SDG 14 Life Below Water

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abstract = "A novel method based on a first-order two-compartment model was used to determine the bioconcentration and toxicokinetic rate constants of six different polycyclic aromatic hydrocarbons (PAHs) in the freshwater isopod Asellus aquaticus, a common species in most European freshwater systems. Numerical integration and iterative parameter estimation techniques were applied to account for time-varying aqueous exposure concentrations. All PAHs exhibited a rapid uptake. Monophasic elimination patterns were observed for benzo[e]pyrene and benzo[a]-pyrene (biological half-life t",

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AU - Cid Montañés, J.F.

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N2 - A novel method based on a first-order two-compartment model was used to determine the bioconcentration and toxicokinetic rate constants of six different polycyclic aromatic hydrocarbons (PAHs) in the freshwater isopod Asellus aquaticus, a common species in most European freshwater systems. Numerical integration and iterative parameter estimation techniques were applied to account for time-varying aqueous exposure concentrations. All PAHs exhibited a rapid uptake. Monophasic elimination patterns were observed for benzo[e]pyrene and benzo[a]-pyrene (biological half-life t

AB - A novel method based on a first-order two-compartment model was used to determine the bioconcentration and toxicokinetic rate constants of six different polycyclic aromatic hydrocarbons (PAHs) in the freshwater isopod Asellus aquaticus, a common species in most European freshwater systems. Numerical integration and iterative parameter estimation techniques were applied to account for time-varying aqueous exposure concentrations. All PAHs exhibited a rapid uptake. Monophasic elimination patterns were observed for benzo[e]pyrene and benzo[a]-pyrene (biological half-life t

U2 - 10.1021/es9800479

DO - 10.1021/es9800479

M3 - Article

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SP - 2409

EP - 2417

JO - Environmental Science and Technology

JF - Environmental Science and Technology

ER -

Toxicokinetics and bioconcentration of polycyclic aromatic hydrocarbons in freshwater isopods

Abstract

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