Tricresylphosphate and the aerotoxic syndrome of flight crew members – current gaps in knowledge

J. de Boer, A. Antelo, I. van der Veen, S.H. Brandsma, N. Lammertse

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

Tricresyl phosphate (TCP), and in particular its tri-ortho substituted isomer (o,o,o-TCP), has been frequently used in aircraft engine oil. Bleed air, provided to the flight deck and cabin can contain traces of TCP. TCP can cause neurotoxic effects in humans. Regularly, airline pilots complain about loss of memory, headaches, dizziness, tunnel vision and other neurotoxic effects. The concentrations of TCP reported in flight deck air (max. ca. 50-100ngm
Original languageEnglish
Pages (from-to)S58-S61
JournalChemosphere
Volume119
DOIs
Publication statusPublished - 2015

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Tritolyl Phosphates
Phosphates
flight
phosphate
Air
Aircraft engines
Aircraft
Memory Disorders
air
Dizziness
Isomers
Headache
engine
Tunnels
aircraft
Oils
tunnel
Data storage equipment
oil

Cite this

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title = "Tricresylphosphate and the aerotoxic syndrome of flight crew members – current gaps in knowledge",
abstract = "Tricresyl phosphate (TCP), and in particular its tri-ortho substituted isomer (o,o,o-TCP), has been frequently used in aircraft engine oil. Bleed air, provided to the flight deck and cabin can contain traces of TCP. TCP can cause neurotoxic effects in humans. Regularly, airline pilots complain about loss of memory, headaches, dizziness, tunnel vision and other neurotoxic effects. The concentrations of TCP reported in flight deck air (max. ca. 50-100ngm",
author = "{de Boer}, J. and A. Antelo and {van der Veen}, I. and S.H. Brandsma and N. Lammertse",
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Tricresylphosphate and the aerotoxic syndrome of flight crew members – current gaps in knowledge. / de Boer, J.; Antelo, A.; van der Veen, I.; Brandsma, S.H.; Lammertse, N.

In: Chemosphere, Vol. 119, 2015, p. S58-S61.

Research output: Contribution to JournalArticleAcademicpeer-review

TY - JOUR

T1 - Tricresylphosphate and the aerotoxic syndrome of flight crew members – current gaps in knowledge

AU - de Boer, J.

AU - Antelo, A.

AU - van der Veen, I.

AU - Brandsma, S.H.

AU - Lammertse, N.

PY - 2015

Y1 - 2015

N2 - Tricresyl phosphate (TCP), and in particular its tri-ortho substituted isomer (o,o,o-TCP), has been frequently used in aircraft engine oil. Bleed air, provided to the flight deck and cabin can contain traces of TCP. TCP can cause neurotoxic effects in humans. Regularly, airline pilots complain about loss of memory, headaches, dizziness, tunnel vision and other neurotoxic effects. The concentrations of TCP reported in flight deck air (max. ca. 50-100ngm

AB - Tricresyl phosphate (TCP), and in particular its tri-ortho substituted isomer (o,o,o-TCP), has been frequently used in aircraft engine oil. Bleed air, provided to the flight deck and cabin can contain traces of TCP. TCP can cause neurotoxic effects in humans. Regularly, airline pilots complain about loss of memory, headaches, dizziness, tunnel vision and other neurotoxic effects. The concentrations of TCP reported in flight deck air (max. ca. 50-100ngm

U2 - 10.1016/j.chemosphere.2014.05.015

DO - 10.1016/j.chemosphere.2014.05.015

M3 - Article

VL - 119

SP - S58-S61

JO - Chemosphere

JF - Chemosphere

SN - 0045-6535

ER -