Tumour necrosis factor-a induces hyperreactivity in tracheal smooth muscle of the guinea-pig in vitro.

H.J. Pennings; K. Kramer; A. Bast; W.A. Buurman; E.F.M. Wouters

doi:10.1183/09031936.98.12010045

Tumour necrosis factor-a induces hyperreactivity in tracheal smooth muscle of the guinea-pig in vitro.

H.J. Pennings, K. Kramer, A. Bast, W.A. Buurman, E.F.M. Wouters

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

Recent studies have implicated a role for tumour necrosis factor-α (TNFα) in the development of the asthmatic reaction. In this study, we examined the influence of TNFα on isotonic contraction of tracheal smooth muscle of the guinea-pig in vitro in response to methacholine. Tracheal rings were incubated with recombinant human (rh)TNFα (3x10

Original language	English
Pages (from-to)	45-49
Journal	European Respiratory Journal
Volume	12
DOIs	https://doi.org/10.1183/09031936.98.12010045
Publication status	Published - 1998

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10.1183/09031936.98.12010045

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title = "Tumour necrosis factor-a induces hyperreactivity in tracheal smooth muscle of the guinea-pig in vitro.",

abstract = "Recent studies have implicated a role for tumour necrosis factor-α (TNFα) in the development of the asthmatic reaction. In this study, we examined the influence of TNFα on isotonic contraction of tracheal smooth muscle of the guinea-pig in vitro in response to methacholine. Tracheal rings were incubated with recombinant human (rh)TNFα (3x10",

author = "H.J. Pennings and K. Kramer and A. Bast and W.A. Buurman and E.F.M. Wouters",

year = "1998",

doi = "10.1183/09031936.98.12010045",

language = "English",

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AU - Pennings, H.J.

AU - Kramer, K.

AU - Bast, A.

AU - Buurman, W.A.

AU - Wouters, E.F.M.

PY - 1998

Y1 - 1998

N2 - Recent studies have implicated a role for tumour necrosis factor-α (TNFα) in the development of the asthmatic reaction. In this study, we examined the influence of TNFα on isotonic contraction of tracheal smooth muscle of the guinea-pig in vitro in response to methacholine. Tracheal rings were incubated with recombinant human (rh)TNFα (3x10

AB - Recent studies have implicated a role for tumour necrosis factor-α (TNFα) in the development of the asthmatic reaction. In this study, we examined the influence of TNFα on isotonic contraction of tracheal smooth muscle of the guinea-pig in vitro in response to methacholine. Tracheal rings were incubated with recombinant human (rh)TNFα (3x10

U2 - 10.1183/09031936.98.12010045

DO - 10.1183/09031936.98.12010045

M3 - Article

SN - 0903-1936

VL - 12

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EP - 49

JO - European Respiratory Journal

JF - European Respiratory Journal

ER -

Tumour necrosis factor-a induces hyperreactivity in tracheal smooth muscle of the guinea-pig in vitro.

Abstract

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