Tumour necrosis factor-a induces hyperreactivity in tracheal smooth muscle of the guinea-pig in vitro.

H.J. Pennings, K. Kramer, A. Bast, W.A. Buurman, E.F.M. Wouters

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

Recent studies have implicated a role for tumour necrosis factor-α (TNFα) in the development of the asthmatic reaction. In this study, we examined the influence of TNFα on isotonic contraction of tracheal smooth muscle of the guinea-pig in vitro in response to methacholine. Tracheal rings were incubated with recombinant human (rh)TNFα (3x10
Original languageEnglish
Pages (from-to)45-49
JournalEuropean Respiratory Journal
Volume12
DOIs
Publication statusPublished - 1998

Fingerprint

Dive into the research topics of 'Tumour necrosis factor-a induces hyperreactivity in tracheal smooth muscle of the guinea-pig in vitro.'. Together they form a unique fingerprint.

Cite this