Ultra-sparse Connectivity within the Lateral Hypothalamus

Denis Burdakov; Mahesh M. Karnani

doi:10.1016/j.cub.2020.07.061

Ultra-sparse Connectivity within the Lateral Hypothalamus

Denis Burdakov, Mahesh M. Karnani^*

^*Corresponding author for this work

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

It is unknown how neural activity is coordinated among lateral hypothalamic area (LH) neurons, which generate fundamental behavioral actions such as attack and evasion. Burdakov and Karnani show there is near-zero local connectivity in the LH, suggesting that incoming synaptic input is integrated primarily within individual neurons.

Original language	English
Pages (from-to)	4063-4070.e2
Journal	Current Biology
Volume	30
Issue number	20
DOIs	https://doi.org/10.1016/j.cub.2020.07.061
Publication status	Accepted/In press - 1 Jan 2020
Externally published	Yes

Keywords

gamma oscillation
lateral hypothalamus
MCH
orexin
patch clamp
synaptic connectivity

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10.1016/j.cub.2020.07.061

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title = "Ultra-sparse Connectivity within the Lateral Hypothalamus",

abstract = "It is unknown how neural activity is coordinated among lateral hypothalamic area (LH) neurons, which generate fundamental behavioral actions such as attack and evasion. Burdakov and Karnani show there is near-zero local connectivity in the LH, suggesting that incoming synaptic input is integrated primarily within individual neurons.",

keywords = "gamma oscillation, lateral hypothalamus, MCH, orexin, patch clamp, synaptic connectivity",

author = "Denis Burdakov and Karnani, {Mahesh M.}",

year = "2020",

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doi = "10.1016/j.cub.2020.07.061",

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AB - It is unknown how neural activity is coordinated among lateral hypothalamic area (LH) neurons, which generate fundamental behavioral actions such as attack and evasion. Burdakov and Karnani show there is near-zero local connectivity in the LH, suggesting that incoming synaptic input is integrated primarily within individual neurons.

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KW - MCH

KW - orexin

KW - patch clamp

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Ultra-sparse Connectivity within the Lateral Hypothalamus

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Keywords

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