Abstract
It is unknown how neural activity is coordinated among lateral hypothalamic area (LH) neurons, which generate fundamental behavioral actions such as attack and evasion. Burdakov and Karnani show there is near-zero local connectivity in the LH, suggesting that incoming synaptic input is integrated primarily within individual neurons.
Original language | English |
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Pages (from-to) | 4063-4070.e2 |
Journal | Current Biology |
Volume | 30 |
Issue number | 20 |
DOIs | |
Publication status | Accepted/In press - 1 Jan 2020 |
Externally published | Yes |
Funding
We thank Jesse Jackson, Rebecca Jordan, Han-Tao Li, Karri Lämsä, and three anonymous referees for helpful comments and discussion. This project has received funding from the European Union's Horizon 2020 research and innovation program under Marie Skłodowska-Curie grant agreement DRIVOME (701986). This work was funded by The Francis Crick Institute, which receives its core funding from Cancer Research UK (FC001055), the UK Medical Research Council (FC001055), and the Wellcome Trust (FC001055). Conceptualization, M.M.K.; Methodology, M.M.K.; Software, M.M.K.; Analysis, M.M.K.; Investigation, M.M.K.; Resources, D.B.; Writing – Original Draft, M.M.K.; Writing – Review & Editing, M.M.K. and D.B.; Funding Acquisition, M.M.K. and D.B. The authors declare no competing interests. We thank Jesse Jackson, Rebecca Jordan, Han-Tao Li, Karri Lämsä, and three anonymous referees for helpful comments and discussion. This project has received funding from the European Union ’s Horizon 2020 research and innovation program under Marie Skłodowska-Curie grant agreement DRIVOME ( 701986 ). This work was funded by The Francis Crick Institute , which receives its core funding from Cancer Research UK ( FC001055 ), the UK Medical Research Council ( FC001055 ), and the Wellcome Trust ( FC001055 ).
Funders | Funder number |
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DRIVOME | |
European Union ’s Horizon 2020 research and innovation program | |
Jesse Jackson | |
Wellcome Trust | |
Francis Crick Institute | |
Horizon 2020 Framework Programme | 701986 |
Medical Research Council | |
Cancer Research UK | FC001055 |
Horizon 2020 |
Keywords
- gamma oscillation
- lateral hypothalamus
- MCH
- orexin
- patch clamp
- synaptic connectivity