Urinary PAH metabolites as biomarkers of exposure in aquatic environments.

G. Fillmann; G.M. Watson; M.J. Howsam; E. Francioni; M. Depledge; J.W. Readman

doi:10.1021/es0350839

Urinary PAH metabolites as biomarkers of exposure in aquatic environments.

G. Fillmann, G.M. Watson, M.J. Howsam, E. Francioni, M. Depledge, J.W. Readman

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

While immunoassays have been extensively applied to evaluate environmental contamination, to date they have rarely been used for the analysis of biological fluids outside of human medicine. These media are important because pollutants such as polycyclic aromatic hydrocarbons (PAHs) and their metabolites become concentrated in tissues, body fluids, and excreta, thereby offering a measure of exposure to biologically available contaminants. Such analyses also provide a nondestructive tool for monitoring exposure. Crabs (Carcinus maenas) were exposed to phenanthrene and pyrene (separately) at concentrations ranging from 0 to 200 μg L

Original language	English
Pages (from-to)	2649-2656
Journal	Environmental Science and Technology
Volume	38
DOIs	https://doi.org/10.1021/es0350839
Publication status	Published - 2004

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abstract = "While immunoassays have been extensively applied to evaluate environmental contamination, to date they have rarely been used for the analysis of biological fluids outside of human medicine. These media are important because pollutants such as polycyclic aromatic hydrocarbons (PAHs) and their metabolites become concentrated in tissues, body fluids, and excreta, thereby offering a measure of exposure to biologically available contaminants. Such analyses also provide a nondestructive tool for monitoring exposure. Crabs (Carcinus maenas) were exposed to phenanthrene and pyrene (separately) at concentrations ranging from 0 to 200 μg L",

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AU - Fillmann, G.

AU - Watson, G.M.

AU - Howsam, M.J.

AU - Francioni, E.

AU - Depledge, M.

AU - Readman, J.W.

PY - 2004

Y1 - 2004

N2 - While immunoassays have been extensively applied to evaluate environmental contamination, to date they have rarely been used for the analysis of biological fluids outside of human medicine. These media are important because pollutants such as polycyclic aromatic hydrocarbons (PAHs) and their metabolites become concentrated in tissues, body fluids, and excreta, thereby offering a measure of exposure to biologically available contaminants. Such analyses also provide a nondestructive tool for monitoring exposure. Crabs (Carcinus maenas) were exposed to phenanthrene and pyrene (separately) at concentrations ranging from 0 to 200 μg L

AB - While immunoassays have been extensively applied to evaluate environmental contamination, to date they have rarely been used for the analysis of biological fluids outside of human medicine. These media are important because pollutants such as polycyclic aromatic hydrocarbons (PAHs) and their metabolites become concentrated in tissues, body fluids, and excreta, thereby offering a measure of exposure to biologically available contaminants. Such analyses also provide a nondestructive tool for monitoring exposure. Crabs (Carcinus maenas) were exposed to phenanthrene and pyrene (separately) at concentrations ranging from 0 to 200 μg L

U2 - 10.1021/es0350839

DO - 10.1021/es0350839

M3 - Article

SN - 0013-936X

VL - 38

SP - 2649

EP - 2656

JO - Environmental Science and Technology

JF - Environmental Science and Technology

ER -

Urinary PAH metabolites as biomarkers of exposure in aquatic environments.

Abstract

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