Urinary PAH metabolites as biomarkers of exposure in aquatic environments.

G. Fillmann, G.M. Watson, M.J. Howsam, E. Francioni, M. Depledge, J.W. Readman

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

While immunoassays have been extensively applied to evaluate environmental contamination, to date they have rarely been used for the analysis of biological fluids outside of human medicine. These media are important because pollutants such as polycyclic aromatic hydrocarbons (PAHs) and their metabolites become concentrated in tissues, body fluids, and excreta, thereby offering a measure of exposure to biologically available contaminants. Such analyses also provide a nondestructive tool for monitoring exposure. Crabs (Carcinus maenas) were exposed to phenanthrene and pyrene (separately) at concentrations ranging from 0 to 200 μg L
Original languageEnglish
Pages (from-to)2649-2656
JournalEnvironmental Science and Technology
Volume38
DOIs
Publication statusPublished - 2004

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    Fillmann, G., Watson, G. M., Howsam, M. J., Francioni, E., Depledge, M., & Readman, J. W. (2004). Urinary PAH metabolites as biomarkers of exposure in aquatic environments. Environmental Science and Technology, 38, 2649-2656. https://doi.org/10.1021/es0350839