Use cases, best practice and reporting standards for metabolomics in regulatory toxicology

Mark R. Viant; Timothy M.D. Ebbels; Richard D. Beger; Drew R. Ekman; David J.T. Epps; Hennicke Kamp; Pim E.G. Leonards; George D. Loizou; James I. MacRae; Bennard van Ravenzwaay; Philippe Rocca-Serra; Reza M. Salek; Tilmann Walk; Ralf J.M. Weber

doi:10.1038/s41467-019-10900-y

Use cases, best practice and reporting standards for metabolomics in regulatory toxicology

Mark R. Viant^*, Timothy M.D. Ebbels, Richard D. Beger, Drew R. Ekman, David J.T. Epps, Hennicke Kamp, Pim E.G. Leonards, George D. Loizou, James I. MacRae, Bennard van Ravenzwaay, Philippe Rocca-Serra, Reza M. Salek, Tilmann Walk, Ralf J.M. Weber

^*Corresponding author for this work

Research output: Contribution to Journal › Article › Academic › peer-review

Abstract

Lack of best practice guidelines currently limits the application of metabolomics in the regulatory sciences. Here, the MEtabolomics standaRds Initiative in Toxicology (MERIT) proposes methods and reporting standards for several important applications of metabolomics in regulatory toxicology.

Original language	English
Article number	3041
Pages (from-to)	1-10
Number of pages	10
Journal	Nature Communications
Volume	10
DOIs	https://doi.org/10.1038/s41467-019-10900-y
Publication status	Published - 10 Jul 2019

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Viant, M. R., Ebbels, T. M. D., Beger, R. D., Ekman, D. R., Epps, D. J. T., Kamp, H., Leonards, P. E. G., Loizou, G. D., MacRae, J. I., van Ravenzwaay, B., Rocca-Serra, P., Salek, R. M., Walk, T., & Weber, R. J. M. (2019). Use cases, best practice and reporting standards for metabolomics in regulatory toxicology. Nature Communications, 10, 1-10. [3041]. https://doi.org/10.1038/s41467-019-10900-y

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AU - Epps, David J.T.

AU - Kamp, Hennicke

AU - Leonards, Pim E.G.

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AU - MacRae, James I.

AU - van Ravenzwaay, Bennard

AU - Rocca-Serra, Philippe

AU - Salek, Reza M.

AU - Walk, Tilmann

AU - Weber, Ralf J.M.

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Use cases, best practice and reporting standards for metabolomics in regulatory toxicology

Abstract

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