Using AI to Steer Brain Regeneration: The Enhanced Regenerative Medicine Paradigm

Gabriella Panuccio, Narayan P. Subramaniyam, Angel Canal-Alonso, Juan M. Corchado, Carlo Ierna

Research output: Chapter in Book / Report / Conference proceedingChapterAcademicpeer-review

Abstract

Enhanced Regenerative Medicine:Brain regeneration is still far from being possible in a controlled and safe approach, as the biological uncertainties linked to stem cell or bioengineered brain tissue grafting represent a major bottleneck. Here, we describe a novel paradigm based on the use of functional biohybrids as grafts, wherein the integration of bioengineered brain tissue within the diseased host brain is steered by a neuromorphic neuroprosthesis and AI. The symbiotic integration of these biological and artificial (hardware and software) components makes up biohybrid neuronics (neural electronics), establishing the enhanced regenerative medicine paradigm. Furthermore, as biomedical brain implantable devices steered by AI raise psychosocial concerns about human enhancement and mind control, we will address these issues from a philosophical perspective.

Original languageEnglish
Title of host publicationBig Data Analysis and Artificial Intelligence for Medical Sciences
PublisherWiley
Pages273-308
Number of pages36
ISBN (Electronic)9781119846567
ISBN (Print)9781119846536
DOIs
Publication statusPublished - 1 Jan 2024

Bibliographical note

Publisher Copyright:
© 2024 selection and editorial matter, David Finkelstein and Andrew Nash; individual owners retain copyright in their own material.

Keywords

  • biohybrid
  • brain
  • epilepsy
  • hippocampus
  • regenerative medicine

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