Abstract
This study examined brain activation during a cognitive inhibition task in patients with schizophrenia following changes in their positive symptoms. A Stroop task was used during functional magnetic resonance imaging in 11 patients with schizophrenia (patient group) and 9 healthy volunteers (control group). At baseline, the patient group showed significantly attenuated activation within the anterior cingulate gyrus, left pre-/postcentral gyrus and inferior frontal junction. At follow-up, there was a significant increase in activation in the left inferior frontal junction associated with a decrease in positive symptoms, suggesting this region plays a role in the development of these symptoms.
Original language | English |
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Pages (from-to) | 373-374 |
Number of pages | 2 |
Journal | British Journal of Psychiatry |
Volume | 194 |
Issue number | 4 |
DOIs | |
Publication status | Published - Apr 2009 |