Using the Stroop task to investigate the neural correlates of symptoms change in schizophrenia

L. Krabbendam, O. O'Daly, L.A. Morley, J van Os, R.M. Murray, S.S. Shergill

Research output: Contribution to JournalArticleAcademicpeer-review

Abstract

This study examined brain activation during a cognitive inhibition task in patients with schizophrenia following changes in their positive symptoms. A Stroop task was used during functional magnetic resonance imaging in 11 patients with schizophrenia (patient group) and 9 healthy volunteers (control group). At baseline, the patient group showed significantly attenuated activation within the anterior cingulate gyrus, left pre-/postcentral gyrus and inferior frontal junction. At follow-up, there was a significant increase in activation in the left inferior frontal junction associated with a decrease in positive symptoms, suggesting this region plays a role in the development of these symptoms.
Original languageEnglish
Pages (from-to)373-374
Number of pages2
JournalBritish Journal of Psychiatry
Volume194
Issue number4
DOIs
Publication statusPublished - Apr 2009

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