Abstract
Background: Aging and type 2 diabetes (T2DM) are associated with an increased risk of sarcopenia. Diagnosis of sarcopenia is commonly done using dual-energy X-ray absorptiometry (DXA) in specialized settings. Another available method for assessing body composition is direct segmental multi-frequency bioelectrical impedance analysis (DSMF-BIA). Here, we examine the accuracy of a DSMF-BIA (InBody-770) for assessing body composition in older adults with T2DM when compared to DXA. Methods: Eighty-four obese/overweight older adults (49 women, 71 ± 5 years) with T2DM who were recruited for the CEV-65 study and had both DSMF-BIA and DXA assessments at baseline were included. The analysis included Bland–Altman plots and intra class correlation coefficients. Sub-analyses were performed according to gender and following 10 weeks of interventions (diet, circuit training, and Empagliflozin). Results: The leg lean mass results according to DSMF-BIA and DXA were 14.76 ± 3.62 kg and 15.19 ± 3.52 kg, respectively, with no difference between devices according to Bland–Altman analyses (p = 0.353). Assessment of appendicular skeletal mass index did not differ between DSMF-BIA and DXA (7.43 vs. 7.47 kg/m2; p = 0.84; ICC = 0.965, p < 0.0001; mean difference −0.068, p = 0.595). Gender and treatment interventions did not modify the accuracy of the DSMF-BIA when compared to DXA. Conclusions: In older adults with T2DM the degree of agreement between DSMF-BIA and DXA, was high, supporting the use of DSMF-BIA to measure muscle mass.
| Original language | English |
|---|---|
| Article number | 45 |
| Pages (from-to) | 1-7 |
| Number of pages | 7 |
| Journal | Nutrition and Diabetes |
| Volume | 12 |
| DOIs | |
| Publication status | Published - 20 Oct 2022 |
Bibliographical note
Funding Information:This work was performed in partial fulfillment of the requirements for a Post-doctoral program by Assaf Buch at the Department of Medicine, Hadassah-Hebrew University Medical Center, Jerusalem, Israel. This work was not supported by any grant or external funding. InBody Co. Ltd did not support this study in any way and has not been involved in the initiation, preparation, and report of this study.
Publisher Copyright:
© 2022, The Author(s).
Funding
This work was performed in partial fulfillment of the requirements for a Post-doctoral program by Assaf Buch at the Department of Medicine, Hadassah-Hebrew University Medical Center, Jerusalem, Israel. This work was not supported by any grant or external funding. InBody Co. Ltd did not support this study in any way and has not been involved in the initiation, preparation, and report of this study.
