Versatility of inner membrane protein biogenesis in Escherichia coli.

L. Froderberg; E.N.G. Houben; J.C. Samuleson; M. Chen; S.K. Park; G.J. Philips; R.E. Dalbey; S. Luirink; J.-W. de Gier

doi:10.1046/j.1365-2958.2003.03346.x

Versatility of inner membrane protein biogenesis in Escherichia coli.

L. Froderberg, E.N.G. Houben, J.C. Samuleson, M. Chen, S.K. Park, G.J. Philips, R.E. Dalbey, S. Luirink, J.-W. de Gier

Research output: Contribution to Journal › Article › Academic

Abstract

To further our understanding of inner membrane protein (IMP) biogenesis in Escherichia coli, we have accomplished the widest in vivo IMP assembly screen so far. The biogenesis of a set of model IMPs covering most IMP structures possible has been studied in a variety of signal recognition particle (SRP), Sec and YidC mutant strains. We show that the assembly of the complete set of model IMPs is assisted (i.e. requires the aid of proteinaceous factors), and that the requirements for assembly of the model IMPs into the inner membrane differ significantly from each other. This indicates that IMP assembly is much more versatile than previously thought.

Original language	English
Pages (from-to)	1015-1027
Number of pages	13
Journal	Molecular Microbiology
Volume	47
DOIs	https://doi.org/10.1046/j.1365-2958.2003.03346.x
Publication status	Published - 2003

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title = "Versatility of inner membrane protein biogenesis in Escherichia coli.",

abstract = "To further our understanding of inner membrane protein (IMP) biogenesis in Escherichia coli, we have accomplished the widest in vivo IMP assembly screen so far. The biogenesis of a set of model IMPs covering most IMP structures possible has been studied in a variety of signal recognition particle (SRP), Sec and YidC mutant strains. We show that the assembly of the complete set of model IMPs is assisted (i.e. requires the aid of proteinaceous factors), and that the requirements for assembly of the model IMPs into the inner membrane differ significantly from each other. This indicates that IMP assembly is much more versatile than previously thought.",

author = "L. Froderberg and E.N.G. Houben and J.C. Samuleson and M. Chen and S.K. Park and G.J. Philips and R.E. Dalbey and S. Luirink and {de Gier}, J.-W.",

year = "2003",

doi = "10.1046/j.1365-2958.2003.03346.x",

language = "English",

volume = "47",

pages = "1015--1027",

journal = "Molecular Microbiology",

issn = "0950-382X",

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TY - JOUR

T1 - Versatility of inner membrane protein biogenesis in Escherichia coli.

AU - Froderberg, L.

AU - Houben, E.N.G.

AU - Samuleson, J.C.

AU - Chen, M.

AU - Park, S.K.

AU - Philips, G.J.

AU - Dalbey, R.E.

AU - Luirink, S.

AU - de Gier, J.-W.

PY - 2003

Y1 - 2003

N2 - To further our understanding of inner membrane protein (IMP) biogenesis in Escherichia coli, we have accomplished the widest in vivo IMP assembly screen so far. The biogenesis of a set of model IMPs covering most IMP structures possible has been studied in a variety of signal recognition particle (SRP), Sec and YidC mutant strains. We show that the assembly of the complete set of model IMPs is assisted (i.e. requires the aid of proteinaceous factors), and that the requirements for assembly of the model IMPs into the inner membrane differ significantly from each other. This indicates that IMP assembly is much more versatile than previously thought.

AB - To further our understanding of inner membrane protein (IMP) biogenesis in Escherichia coli, we have accomplished the widest in vivo IMP assembly screen so far. The biogenesis of a set of model IMPs covering most IMP structures possible has been studied in a variety of signal recognition particle (SRP), Sec and YidC mutant strains. We show that the assembly of the complete set of model IMPs is assisted (i.e. requires the aid of proteinaceous factors), and that the requirements for assembly of the model IMPs into the inner membrane differ significantly from each other. This indicates that IMP assembly is much more versatile than previously thought.

U2 - 10.1046/j.1365-2958.2003.03346.x

DO - 10.1046/j.1365-2958.2003.03346.x

M3 - Article

SN - 0950-382X

VL - 47

SP - 1015

EP - 1027

JO - Molecular Microbiology

JF - Molecular Microbiology

ER -

Versatility of inner membrane protein biogenesis in Escherichia coli.

Abstract

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