Vibrational circular dichroism studies of exceptionally strong chirality inducers in liquid crystals

Mark A.J. Koenis, Valentin P. Nicu, Lucas Visscher, Christian Kuehn, Matthias Bremer, Mireille Krier, Harald Untenecker, Ulmas Zhumaev, Bernd Küstner, Wybren Jan Buma*

*Corresponding author for this work

Research output: Contribution to JournalReview articleAcademicpeer-review


7,7′-Disubstituted 2,2′-methylenedioxy-1,1′-binaphthyls are highly efficient chirality inducers in nematic liquid crystals. The absolute configuration of these compounds is, however, hard to determine as they only crystallize as racemic mixtures. In this work a Vibrational Circular Dichroism (VCD) study is reported that provides an unambiguous determination of the absolute configuration of these compounds. An in-depth General Coupled Oscillator (GCO) analysis of the source of the VCD signal reveals that the unusual structure of these binaphthyl compounds inherently leads to strong and robust VCD bands. Combined with linear transit calculations, our VCD studies allow for the determination of key structural parameters.

Original languageEnglish
Pages (from-to)10021-10028
Number of pages8
JournalPhysical Chemistry Chemical Physics
Issue number16
Early online date9 Apr 2021
Publication statusPublished - 28 Apr 2021

Bibliographical note

Funding Information:
M. A. J. K., L. V. and W. J. B. acknowledge financial support from NWO in the framework of the Fund New Chemical Innovations (NWO Project No. 731.014.209). V. P. N. acknowledges funding from UEFISCDI (PN-III-P4-ID-PCE-2020-2783, contract no. PCE 190/2021).

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Copyright 2021 Elsevier B.V., All rights reserved.


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